Coccobacillus in the context of "Bordetella pertussis"


Coccobacillus in the context of "Bordetella pertussis"

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⭐ Core Definition: Coccobacillus

Bacterial cellular morphologies are the shapes that are characteristic of various types of bacteria and often key to their identification. Their direct examination under a light microscope enables the classification of these bacteria (and archaea).

Generally, the basic morphologies are spheres (coccus) and round-ended cylinders or rod shaped (bacillus). But, there are also other morphologies such as helically twisted cylinders (example Spirochetes), cylinders curved in one plane (selenomonads) and unusual morphologies (the square, flat box-shaped cells of the Archaean genus Haloquadratum). Other arrangements include pairs, tetrads, clusters, chains and palisades.

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👉 Coccobacillus in the context of Bordetella pertussis

Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus bacterium of the genus Bordetella. It is the causative agent of pertussis or whooping cough. Despite widespread vaccination, B. pertussis continues to cause illness and death worldwide due to declining immunity and pathogen adaptation. Its virulence factors include pertussis toxin, adenylate cyclase toxin, filamentous haemagglutinin, pertactin, fimbria, and tracheal cytotoxin.

B. pertussis is an obligate human pathogen and is transmitted through airborne droplets. The disease's incubation period averages 7–10 days, however the range is anywhere from 6–20 days. The bacterium attaches to the ciliated epithelial cells lining the respiratory tract using specialized surface proteins to remain in place. It then releases toxins that disrupt normal cellular functions and cause symptoms in its human host, the only known reservoir for B. pertussis.

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