La Litera (Spanish: [la liˈteɾa]) or La Llitera (Catalan: [la ʎiˈteɾa]) (Aragonese: A Litera) is an Aragonese comarca in the south-east of the province of Huesca.
Its cultural capital is Tamarite de Litera, its administrative capital is Binefar and it borders the comarques of Ribagorza, Somontano de Barbastro, Cinca Medio, Bajo Cinca in Aragon and Noguera and Segrià in Catalonia.