The A6 is one of the main north–south roads in England. It runs from Luton in Bedfordshire to Carlisle in Cumbria, although it formerly started at a junction with the A1 at Barnet in north London, and is described as running from London to Carlisle.
Running north-west from Luton, the road passes through Bedford, bypasses Rushden, Kettering and Market Harborough, continues through Leicester, Loughborough, Derby and Matlock before passing through the Peak District to Bakewell, Buxton, Stockport, Manchester, Salford, Chorley, Preston, Lancaster, Kendal and Penrith before reaching Carlisle.