Capillary in the context of "Circumventricular organs"

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⭐ Core Definition: Capillary

A capillary is a small blood vessel, from 5 to 10 micrometres in diameter, and is part of the microcirculation system. Capillaries are microvessels and the smallest blood vessels in the body. They are composed of only the tunica intima (the innermost layer of an artery or vein), consisting of a thin wall of simple squamous endothelial cells. They are the site of the exchange of many substances from the surrounding interstitial fluid, and they convey blood from the smallest branches of the arteries (arterioles) to those of the veins (venules). Other substances which cross capillaries include water, oxygen, carbon dioxide, urea, glucose, uric acid, lactic acid and creatinine. Lymph capillaries connect with larger lymph vessels to drain lymphatic fluid collected in microcirculation.

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👉 Capillary in the context of Circumventricular organs


Circumventricular organs (CVOs) (circum-: around ; ventricular: of ventricle) are structures in the brain characterized by their extensive and highly permeable capillaries, unlike those in the rest of the brain where there exists a blood–brain barrier (BBB) at the capillary level. Although the term "circumventricular organs" was originally proposed in 1958 by Austrian anatomist Helmut O. Hofer concerning structures around the brain ventricular system, the penetration of blood-borne dyes into small specific CVO regions was discovered in the early 20th century. The permeable CVOs enabling rapid neurohumoral exchange include the subfornical organ (SFO), the area postrema (AP), the vascular organ of lamina terminalis (VOLT — also known as the organum vasculosum of the lamina terminalis (OVLT)), the median eminence, the pituitary neural lobe, and the pineal gland.

The circumventricular organs are midline structures around the third and fourth ventricles that are in contact with blood and cerebrospinal fluid, and they facilitate special types of communication between the central nervous system and peripheral blood. Additionally, they are an integral part of neuroendocrine function. Highly permeable capillaries allow the CVOs to act as an alternative route for peptides and hormones in the neural tissue to sample from and secrete to circulating blood. CVOs also have roles in body fluid regulation, cardiovascular functions, immune responses, thirst, feeding behavior and reproductive behavior.

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Capillary in the context of Grey matter

Grey matter (gray matter in American English) is a major component of the central nervous system, consisting of neuronal cell bodies, neuropil (dendrites and unmyelinated axons), glial cells (astrocytes and oligodendrocytes), synapses, and capillaries. Grey matter is distinguished from white matter in that it contains numerous cell bodies and relatively few myelinated axons, while white matter contains relatively few cell bodies and is composed chiefly of long-range myelinated axons. The colour difference arises mainly from the whiteness of myelin. In living tissue, grey matter actually has a very light grey colour with yellowish or pinkish hues, which come from capillary blood vessels and neuronal cell bodies.

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Capillary in the context of Red blood cell

Red blood cells (RBCs), referred to as erythrocytes (from Ancient Greek erythros 'red' and kytos 'hollow vessel', with -cyte translated as 'cell' in modern usage) in academia and medical publishing, also known as red cells, erythroid cells, and rarely haematids, are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system. Erythrocytes take up oxygen in the lungs, or in fish the gills, and release it into tissues while squeezing through the body's capillaries.

The cytoplasm of a red blood cell is rich in hemoglobin (Hb), an iron-containing biomolecule that can bind oxygen and is responsible for the red color of the cells and the blood. Each human red blood cell contains approximately 270 million hemoglobin molecules. The cell membrane is composed of proteins and lipids, and this structure provides properties essential for physiological cell function such as deformability and stability of the blood cell while traversing the circulatory system and specifically the capillary network.

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Capillary in the context of Lymphatic vessel

The lymphatic vessels (or lymph vessels or lymphatics) are thin-walled vessels (tubes), structured like blood vessels, that carry lymph. As part of the lymphatic system, lymph vessels are complementary to the cardiovascular system. Lymph vessels are lined by endothelial cells, and have a thin layer of smooth muscle, and adventitia that binds the lymph vessels to the surrounding tissue. Lymph vessels are devoted to the propulsion of the lymph from the lymph capillaries, which are mainly concerned with the absorption of interstitial fluid from the tissues. Lymph capillaries are slightly bigger than their counterpart capillaries of the vascular system. Lymph vessels that carry lymph to a lymph node are called afferent lymph vessels, and those that carry it from a lymph node are called efferent lymph vessels, from where the lymph may travel to another lymph node, may be returned to a vein, or may travel to a larger lymph duct. Lymph ducts drain the lymph into one of the subclavian veins and thus return it to general circulation.

The vessels that bring lymph away from the tissues and towards the lymph nodes can be classified as afferent vessels. These afferent vessels then drain into the subcapsular sinus. The efferent vessels that bring lymph from the lymphatic organs to the nodes bringing the lymph to the right lymphatic duct or the thoracic duct, the largest lymph vessel in the body. These vessels drain into the right and left subclavian veins, respectively. There are far more afferent vessels bringing in lymph than efferent vessels taking it out to allow for lymphocytes and macrophages to fulfill their immune support functions. The lymphatic vessels contain valves.

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Capillary in the context of Pulmonary alveolus

A pulmonary alveolus (pl.alveoli; from Latin alveolus 'little cavity'), also called an air sac or air space, is one of millions of hollow, distensible cup-shaped cavities in the lungs where pulmonary gas exchange takes place. Oxygen is exchanged for carbon dioxide at the blood–air barrier between the alveolar air and the pulmonary capillary. Alveoli make up the functional tissue of the mammalian lungs known as the lung parenchyma, which takes up 90 percent of the total lung volume.

Alveoli are first located in the respiratory bronchioles that mark the beginning of the respiratory zone. They are located sparsely in these bronchioles, line the walls of the alveolar ducts, and are more numerous in the blind-ended alveolar sacs. The acini are the basic units of respiration, with gas exchange taking place in all the alveoli present. The alveolar membrane is the gas exchange surface, surrounded by a network of capillaries. Oxygen is diffused across the membrane into the capillaries and carbon dioxide is released from the capillaries into the alveoli to be breathed out.

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Capillary in the context of Hematophagy

Hematophagy (sometimes spelled haematophagy or hematophagia) is the practice by certain animals of feeding on blood (from the Greek words αἷμα haima "blood" and φαγεῖν phagein "to eat"). Since blood is a fluid tissue rich in nutritious proteins and lipids that can be taken without great effort, hematophagy is a preferred form of feeding for many small animals, such as worms and arthropods. Some intestinal nematodes, such as Ancylostomatids, feed on blood extracted from the capillaries of the gut, and about 75 percent of all species of leeches (e.g., Hirudo medicinalis) are hematophagous. The spider Evarcha culicivora feeds indirectly on vertebrate blood by specializing on blood-filled female mosquitoes as their preferred prey. Some fish, such as lampreys and candirus; mammals, especially vampire bats; and birds, including the vampire finch, Hood mockingbird, Tristan thrush, and oxpeckers, also practice hematophagy.

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Capillary in the context of Livor mortis

Livor mortis (from Latin līvor 'bluish color, bruise' and mortis 'of death'), postmortem lividity (from Latin post mortem 'after death' and lividitas 'black and blueness'), hypostasis (from Greek ὑπό (hypo) 'under, beneath' and στάσις (stasis) 'a standing') or suggillation, is the second stage of death and one of the signs of death. It is a settling of the blood in the lower, or dependent, portion of the body postmortem, causing a purplish red discoloration of the skin. When the heart stops functioning and is no longer agitating the blood, heavy red blood cells sink through the serum by action of gravity. The blood travels faster in warmer conditions and slower in colder conditions.

Livor mortis starts within 20–30 minutes, but is usually not observable by the human eye until two hours after death. The size of the patches increases in the next three to six hours. Fixation will begin to occur during this timeframe, causing the patches to be unaltered due to movement. Maximum lividity will occur between eight and twelve hours after death. Areas of blood pooling in contact with the ground will blanch, or remain white. The blood pools into the interstitial tissues of the body. The intensity of the color depends upon the amount of reduced haemoglobin in the blood. The discoloration does not occur in the areas of the body that are in contact with the ground or another object, in which capillaries are compressed.

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