The calle de Serrano, or simply Serrano, is a street in Madrid, Spain. It is noted as location for luxury flagship stores.
The urbanisation took off in 1863, with the construction of the first housing in the street. Initially known as Bulevar Narváez (Narváez Boulevard), the street received its current name following the 1868 Glorious Revolution, during which the namesake, the General Serrano (who had lived in the street), took a leading role. In the 2010s the street became one the favourite grounds for real estate operations of Venezuelan fortunes.