Edward Thurlow Weed (November 15, 1797 – November 22, 1882) was an American printer, newspaper publisher, and Whig and Republican politician. He was the principal political advisor to prominent New York politician William H. Seward and was instrumental in the presidential nominations of William Henry Harrison (1840), Zachary Taylor (1848), and John C. Frémont (1856).
Born in Cairo, New York, Weed apprenticed as a printer under William Williams and served with him in the War of 1812 before winning election to the New York State Assembly. He met Seward in the assembly, and they formed a close political alliance that lasted for several decades. Weed and Seward became leaders of the New York Anti-Masonic Party, and Weed established the Albany Evening Journal as the party's main newspaper. Weed supported the American System of Henry Clay and helped establish the Whig Party in the 1830s. He helped Seward win election as Governor of New York and supported the successful presidential candidacies of Harrison and Taylor.