The COVID-19 vaccination campaign in the United States was a mass immunization campaign for the COVID-19 pandemic in the United States. The Food and Drug Administration (FDA) first granted emergency use authorization to the Pfizer–BioNTech vaccine on December 10, 2020, and mass vaccinations began four days later. The Moderna vaccine was granted emergency use authorization on December 17, 2020, and the Janssen (Johnson & Johnson) vaccine was granted emergency use authorization on February 27, 2021. It was not until April 19, 2021, that all U.S. states had opened vaccine eligibility to residents aged 16 and over. On May 10, 2021, the FDA approved the Pfizer-BioNTech vaccine for adolescents aged 12 to 15. On August 23, 2021, the FDA granted full approval to the Pfizer–BioNTech vaccine for individuals aged 16 and over.
The U.S. government began the campaign under the presidency of Donald Trump with Operation Warp Speed, a public–private partnership to expedite the development and manufacturing of COVID-19 vaccines. Joe Biden became the new president of the United States on January 20, 2021. Biden had an immediate goal of administering 100 million vaccine doses within his first hundred days in office, and signed an executive order which increased supplies for vaccination. This goal was met on March 19, 2021. On March 25, 2021, he announced he would increase the goal to 200 million within his first 100 days in office. This goal was reached on April 21, 2021.