La Défense station (French pronunciation: [la defɑ̃s]) is a station of the Transilien (Réseau Saint-Lazare) suburban rail lines, RER commuter rail network, Paris Métro, as well as a stop of the Île-de-France tram network. In the future, Paris Metro Line 15 of Grand Paris Express will pass through here, making it a huge railway hub. It is underneath the Grande Arche building in La Défense, the business district just west of Paris. The station is the western terminus of Métro Line 1 and connects the RER A line to the Métro Line 1 station since 1992, the Line 2 tramway since 1994 and SNCF (Transilien) train station. It is also attached to a major shopping centre. There are over 25 million entries and exits each year. A temporary special SNCF service began in April 1959 to serve the newly-built Centre of New Industries and Technologies (CNIT); the RER entered service on 19 January 1970. The RER E station built under the CNIT opened on 6 May 2024.
Highlights on the surface nearby include the monumental Grande Arche, skyscrapers that host the headquarters of important French and foreign companies, and works of urban art such as Le Pouce by César Baldaccini. From the central esplanade the Arc de Triomphe can be seen further down the Axe historique. Until May 2004, this part of La Défense hosted an information centre of the European Union managed by the European Parliament. Like the district it serves, the station takes its name from the 19th-century statue La Défense de Paris, commemorating the Franco-Prussian War.