Kuzguncuk is a neighbourhood in the municipality and district of Üsküdar, Istanbul Province, Turkey. Its population is 4,151 (2022). It is on the Asian side of the Bosphorus. The neighborhood is centered on a valley opening to the Bosphorus and is somewhat isolated from the main part of the city, being surrounded by nature preserves, cemeteries, and a military installation. It is a quiet neighborhood with streets lined with antique Ottoman wooden houses.
Kuzguncuk is bordered on the north by Beylerbeyi, on the east by Burhaniye, on the south by İcadiye and Sultantepe, and on the west by the Bosphorus. On the other side of the Bosphorus is Beşiktaş. The Otoyol 1 highway separates the neighborhood from Burhaniye.