Bukhara Region is a region of Uzbekistan located in the southwest of the country. The Kyzyl Kum desert takes up a large portion of its territory. It borders Turkmenistan, Navoiy Region, Qashqadaryo Region, a small part of the Xorazm Region, and the Karakalpakstan Republic. It covers an area of 40,216 km. The population is estimated at 1,976,823 (as of 2022), with 63% living in rural areas.
Buxoro Region is divided into 11 administrative districts and two district-level cities. The capital is Bukhara, with a population of around 284,100 (as of 2021). Other major towns include Olot, Qorakoʻl (Karakul), Galaosiyo, Gazli, Gʻijduvon (pop. ~40,600, as of late 2005), Kogon (pop. ~62,300, as of 2021), Romitan, Shofirkon, and Vobkent.