Buffalo–Niagara Falls metropolitan area in the context of Niagara County, New York

Buffalo is a city in the U.S. state of New York. It lies in Western New York at the eastern end of Lake Erie and at the head of the Niagara River on the Canada–United States border. It is the second-most populous city in New York, with a population of 278,349 at the 2020 census. The Buffalo–Niagara Falls metropolitan area, with over 1.16 million residents, is the 51st-largest metropolitan area in the United States. Buffalo is the county seat of Erie County.

Before the 17th century, the region was inhabited by nomadic Paleo-Indians who were succeeded by the Neutral, Erie, and Iroquois nations. In the early 17th century, the French began to explore the region. In the 18th century, Iroquois land surrounding Buffalo Creek was ceded through the Holland Land Purchase, and a small village was established at its headwaters. Buffalo was selected as the terminus of the Erie Canal in 1825, which led to its incorporation in 1832 and stimulated its growth as the primary inland port between the Great Lakes and Atlantic Ocean. Transshipment made Buffalo the world's largest grain port in that era. After the coming of railroads greatly reduced the canal's importance, the city became the second-largest railway hub (after Chicago), and the city came to be dominated by steel production by the 20th century. Later, deindustrialization and the opening of the St. Lawrence Seaway saw the city's economy decline and diversify. It developed its service industries, such as health care, retail, tourism, logistics, and education, while retaining some manufacturing.

Niagara Falls is a city in Niagara County, New York, United States. As of the 2020 census, the city had a total population of 48,671. It is adjacent to the Niagara River, across from the city of Niagara Falls, Ontario, and named after the famed Niagara Falls which they share. The city is within the Buffalo–Niagara Falls metropolitan area and the Western New York region.

While the city was formerly inhabited by Native Americans, Europeans who migrated to the Niagara Falls in the mid-17th century began to open businesses and develop infrastructure. Later in the 18th and 19th centuries, scientists and businessmen began harnessing the power of the Niagara River for electricity and the city began to attract manufacturers and other businesses drawn by the promise of inexpensive hydroelectric power. After the 1960s, however, the city and region experienced an economic decline. As industries left the region, affluent and middle-class families relocated from Niagara Falls to other metropolitan areas around the country.

Cattaraugus County (locally known as Catt County) is a county in Western New York, with one side bordering Pennsylvania. As of the United States 2020 census, the population was 77,042. The county seat is Little Valley. The county was created in 1808 and later organized in 1817. The county is part of the Western New York region of the state.

Cattaraugus County comprises the Olean, NY Micropolitan Statistical Area, which is included in the Buffalo-Cheektowaga-Olean, NY Combined Statistical Area. Within its boundaries are the Allegany Indian Reservation of the Seneca Nation of New York, and the Allegany State Park. The Allegheny River runs through the county.