The Ronald Reagan Building and International Trade Center, named after former United States president Ronald Reagan, is located in downtown Washington, D.C., and was the first federal building in Washington designed for both governmental and private sector purposes. It is the second largest federal building after the Pentagon At the time it was built, the Ronald Reagan Building was the most expensive federal building ever constructed, at a cost of $768 million.
Each of the organizations located in the Pennsylvania Avenue building are dedicated to international trade and global relations. Organizations headquartered in this building include U.S. Customs and Border Protection (CBP), and the Woodrow Wilson International Center for Scholars. The U.S. Agency for International Development (USAID) was a tenant for many years until November, 2025, when it was no longer an independent agency. The first private sector lease was signed with investment banking firm Quarterdeck Investment Partners, Inc. The building hosts conferences, trade shows, cultural events, and outdoor concerts. Post-9/11, security requirements for high-profile federal buildings have limited the amount of public access anticipated by the center's designers.