Constantine the Great's (272–337) relationship with the four Bishops of Rome during his reign is an important component of the history of the Papacy, and more generally the history of the Catholic Church.
The legend surrounding Constantine I's victory in the Battle of the Milvian Bridge (312) relates his vision of the Chi Rho (☧) and the text in hoc signo vinces in the sky and his reproducing this symbol on the shields of his troops. The following year Constantine and Licinius proclaimed the toleration of Christianity with the Edict of Milan, and in 325 Constantine convened and presided over the First Council of Nicaea, the first ecumenical council. None of this, however, has particularly much to do with the popes, who did not even attend the Council; in fact, the first bishop of Rome to be contemporaneously referred to as "Pope" (πάππας, or pappas) is Damasus I (366-384). Moreover, between 324 and 330, he built Constantinople as a new capital for the empire, and—with no apologies to the Roman community of Christians—relocated key Roman families and translated many Christian relics to the new churches.