Biomaterial in the context of "Synthetic biology"

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⭐ Core Definition: Biomaterial

A biomaterial is a substance that has been engineered to interact with biological systems for a medical purpose – either a therapeutic (treat, augment, repair, or replace a tissue function of the body) or a diagnostic one. The corresponding field of study is called biomaterials science or biomaterials engineering. It has experienced steady growth over its history, with many companies investing large amounts of money into the development of new products. Biomaterials science encompasses elements of medicine, biology, chemistry, tissue engineering and materials science.

A biomaterial is different from a biological material, such as bone, that is produced by a biological system. However, "biomaterial" and "biological material" are often used interchangeably. Further, the word "bioterial" has been proposed as a potential alternate word for biologically produced materials such as bone, or fungal biocomposites. Additionally, care should be exercised in defining a biomaterial as biocompatible, since it is application-specific. A biomaterial that is biocompatible or suitable for one application may not be biocompatible in another.

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👉 Biomaterial in the context of Synthetic biology

Synthetic biology (SynBio) is a multidisciplinary field of science that focuses on living systems and organisms. It applies engineering principles to develop new biological parts, devices, and systems or to redesign existing systems found in nature.

It is a branch of science that encompasses a broad range of methodologies from various disciplines, such as biochemistry, biotechnology, biomaterials, material science/engineering, genetic engineering, molecular biology, molecular engineering, systems biology, membrane science, biophysics, chemical and biological engineering, electrical and computer engineering, control engineering and evolutionary biology.

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Biomaterial in the context of Hair

Hair is a protein filament that grows from follicles found in the dermis. Hair is one of the defining characteristics of mammals.The human body, apart from areas of glabrous skin, is covered in follicles which produce thick terminal and fine vellus hair. Most common interest in hair is focused on hair growth, hair types, and hair care, but hair is also an important biomaterial primarily composed of protein, notably alpha-keratin.

Attitudes towards different forms of hair, such as hairstyles and hair removal, vary widely across different cultures and historical periods, but it is often used to indicate a person's personal beliefs or social position, such as their age, gender, or religion.

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Biomaterial in the context of Laboratory specimen

A laboratory specimen is sometimes a biological specimen of a medical patient's tissue, fluids, or other samples used for laboratory analysis to assist in differential diagnosis or staging of a disease process. These specimens are often the most reliable method of diagnosis, depending on the ailment. For example, breast cancer biopsies, performed on laboratory specimens of breast tissue, yield just a 2% rate of incorrect diagnosis. Laboratory specimens may also include feces.

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Biomaterial in the context of Soft matter

Soft matter or soft condensed matter is a type of matter that can be deformed or structurally altered by thermal or mechanical stress which is of similar magnitude to thermal fluctuations.

The science of soft matter is a subfield of condensed matter physics. Soft materials include liquids, colloids, polymers, foams, gels, granular materials, liquid crystals, flesh, and a number of biomaterials. These materials share an important common feature in that predominant physical behaviors occur at an energy scale comparable with room temperature thermal energy (of order of kT), and that entropy is considered the dominant factor. At these temperatures, quantum aspects are generally unimportant. When soft materials interact favorably with surfaces, they become squashed without an external compressive force.

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Biomaterial in the context of Implant (medicine)

An implant is a medical device manufactured to replace a missing biological structure, support a damaged biological structure, or enhance an existing biological structure. For example, an implant may be a rod, used to strengthen weak bones. Medical implants are human-made devices, in contrast to a transplant, which is a transplanted biomedical tissue. The surface of implants that contact the body might be made of a biomedical material such as titanium, silicone, or apatite depending on what is the most functional. In 2018, for example, American Elements developed a nickel alloy powder for 3D printing robust, long-lasting, and biocompatible medical implants. In some cases implants contain electronics, e.g. artificial pacemaker and cochlear implants. Some implants are bioactive, such as subcutaneous drug delivery devices in the form of implantable pills or drug-eluting stents.

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Biomaterial in the context of Meat alternative

A meat alternative or meat substitute, also referred to as a plant-based meat, mock meat, or alternative protein, is a food product that is made from vegetarian or vegan ingredients and is consumed as a replacement for meat. The objective of meat alternatives is to replicate the qualities of meat, including its mouthfeel, flavor, and appearance. Plant- and fungus-based substitutes are frequently made with soy (e.g., tofu, tempeh, and textured vegetable protein), but may also be made from wheat gluten as in seitan, pea protein as in the Beyond Burger, or mycoprotein as in Quorn. Alternative protein foods can also be made by precision fermentation, where single cell organisms such as yeast produce specific proteins using a carbon source; or can be grown by culturing animal cells outside an animal, based on tissue engineering techniques. The ingredients of meat alternatives include 50–80% water, 10–25% textured vegetable proteins, 4–20% non-textured proteins, 0–15% fat and oil, 3-10% flavors/spices, 1–5% binding agents, and 0–0.5% coloring agents.  

Meatless tissue engineering involves the cultivation of stem cells on natural or synthetic scaffolds to create meat-like products. Scaffolds can be made from various materials, including plant-derived biomaterials, synthetic polymers, animal-based proteins, and self-assembling polypeptides. It is these 3D scaffold-based methods that provide a specialized structural environment for cellular growth. Alternatively, scaffold-free methods promote cell aggregation, allowing cells to self-organize into tissue-like structures.

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