Biological activity in the context of "Peripheral membrane protein"

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👉 Biological activity in the context of Peripheral membrane protein

Peripheral membrane proteins, or extrinsic membrane proteins, are membrane proteins that adhere only temporarily to the biological membrane with which they are associated. These proteins attach to integral membrane proteins, or penetrate the peripheral regions of the lipid bilayer. The regulatory protein subunits of many ion channels and transmembrane receptors, for example, may be defined as peripheral membrane proteins. In contrast to integral membrane proteins, peripheral membrane proteins tend to collect in the water-soluble component, or fraction, of all the proteins extracted during a protein purification procedure. Proteins with GPI anchors are an exception to this rule and can have purification properties similar to those of integral membrane proteins.

The reversible attachment of proteins to biological membranes has shown to regulate cell signaling and many other important cellular events, through a variety of mechanisms. For example, the close association between many enzymes and biological membranes may bring them into close proximity with their lipid substrate(s). Membrane binding may also promote rearrangement, dissociation, or conformational changes within many protein structural domains, resulting in an activation of their biological activity. Additionally, the positioning of many proteins are localized to either the inner or outer surfaces or leaflets of their resident membrane.This facilitates the assembly of multi-protein complexes by increasing the probability of any appropriate protein–protein interactions.

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Biological activity in the context of Controlled substance

A controlled substance is generally a drug or chemical whose manufacture, possession, and use is regulated by a government, such as illicitly-obtained drugs or prescription medications that are designated by law. Some treaties, notably the Single Convention on Narcotic Drugs, the Convention on Psychotropic Substances, and the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances, provide internationally agreed-upon "schedules" of controlled substances, which have been incorporated into national laws; however, national laws usually significantly expand on these international conventions.

Some precursor chemicals used for the illegal production of 'controlled drugs' are also controlled substances in many countries, even though they may lack the pharmacological effects of the drugs themselves. Substances are classified according to schedules and consist primarily of potentially psychoactive substances and anabolic steroids. The controlled substances do not include many prescription items such as antibiotics.

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Biological activity in the context of Molecular structure

Molecular geometry is the three-dimensional arrangement of the atoms that constitute a molecule. It includes the general shape of the molecule as well as bond lengths, bond angles, torsional angles and any other geometrical parameters that determine the position of each atom.

Molecular geometry influences several properties of a substance including its reactivity, polarity, phase of matter, color, magnetism and biological activity. The angles between bonds that an atom forms depend only weakly on the rest of a molecule, i.e. they can be understood as approximately local and hence transferable properties.

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Biological activity in the context of Pesticide formulation

The biological activity of a pesticide, be it chemical or biological in nature, is determined by its active ingredient (AI - also called the active substance). Pesticide products very rarely consist of the pure active ingredient. The AI is usually formulated with other materials (adjuvents and co-formulants) and this is the product as sold, but it may be further diluted in use. Formulations improve the properties of a chemical for handling, storage, application and may substantially influence effectiveness and safety.

Formulation types are categorised into two-letter international formulation codes: (e.g. GR: granules), which must be used when registering a new pesticide product. Croplife maintains this list, which in the 7th update (2017) contains 65 formulation codes and 29 codes which are no longer used.

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Biological activity in the context of Ingredient

In a general sense, an ingredient is a substance which forms part of a mixture. In cooking, recipes specify which ingredients are used to prepare a dish, and the term may also refer to a specific food item in relation to its use in different recipes. Many commercial products contain secret ingredients purported to make them better than competing products. In the pharmaceutical industry, an active ingredient is the ingredient in a formulation which invokes biological activity.

National laws usually require prepared food products to display a list of ingredients and specifically require that certain additives be listed. Law typically requires that ingredients be listed according to their relative weight within the product.

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Biological activity in the context of Environmental chemistry

Environmental chemistry is the scientific study of the chemical and biochemical phenomena that occur in natural places. It should not be confused with green chemistry, which seeks to reduce potential pollution at its source. It can be defined as the study of the sources, reactions, transport, effects, and fates of chemical species in the air, soil, and water environments; and the effect of human activity and biological activity on these. Environmental chemistry is an interdisciplinary science that includes atmospheric, aquatic and soil chemistry, as well as heavily relying on analytical chemistry and being related to environmental and other areas of science.

Environmental chemistry involves first understanding how the uncontaminated environment works, which chemicals in what concentrations are present naturally, and with what effects. Without this it would be impossible to accurately study the effects humans have on the environment through the release of chemicals.

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Biological activity in the context of Implant (medicine)

An implant is a medical device manufactured to replace a missing biological structure, support a damaged biological structure, or enhance an existing biological structure. For example, an implant may be a rod, used to strengthen weak bones. Medical implants are human-made devices, in contrast to a transplant, which is a transplanted biomedical tissue. The surface of implants that contact the body might be made of a biomedical material such as titanium, silicone, or apatite depending on what is the most functional. In 2018, for example, American Elements developed a nickel alloy powder for 3D printing robust, long-lasting, and biocompatible medical implants. In some cases implants contain electronics, e.g. artificial pacemaker and cochlear implants. Some implants are bioactive, such as subcutaneous drug delivery devices in the form of implantable pills or drug-eluting stents.

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Biological activity in the context of Ingredients

In a general sense, an ingredient is a substance which forms part of a mixture. In cooking, recipes specify which ingredients are used to prepare a dish, and the term may also refer to a specific food item in relation to its use in different recipes. Many commercial products contain secret ingredients purported to make them better than competing products. In the pharmaceutical industry, an active ingredient is the ingredient in a formulation which invokes biological activity.

National laws usually require prepared food products to display a list of ingredients and specifically require that certain additives be listed. In the European Union, food labeling regulations also mandate that allergens such as nuts, milk, and gluten be clearly emphasized within the ingredient list to protect consumers.

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Biological activity in the context of Active substance

An active ingredient is any ingredient that provides biologically active or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the body of humans or animals.

The similar terms active pharmaceutical ingredient (abbreviated as API) and bulk active are also used in medicine. The term active substance may be used to describe the effective chemical used to control bacteria or pests.

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