The Battle of Damghan (Persian: نبرد دامغان) or Battle of Mehmandoost (Persian: نبرد مهماندوست) was fought on September 29 to October 5, 1729, near the city of Damghan. It resulted in an overwhelming victory for Nader and the Safavid cause he had taken up, though by itself it did not end Ashraf's rule in Iran, it was a significant triumph which led to further successes in the following engagements of the campaign to restore Tahmasp II to the throne. The battle was followed by another one in Murcheh-Khort, a village near Isfahan. Nader's forces were victorious in both battles, which led him to remove the Ghilzai Afghan dynasty from their short stay on the Persian throne. The Hotakis were forced back to their territory in what is now southern Afghanistan.
The Battle of Damghan proved the supremacy of Nader's artillery-dependent military system compared to the old, exclusively cavalry-based system utilised by the Afghans. Despite losing this battle, Hotak tried to come back in the Battle of Murcheh-Khort, relying on guns and artillerymen from the Ottomans. But in the Battle of Murcheh-Khort Ashraf Hotaki lost to the superior army of Nader. Hotak was killed in 1730, and Nader succeeded in overthrowing the Hotaki dynasty in 1738.