Adana massacre in the context of Second Constitutional Era (Ottoman Empire)

The Armenian genocide was the systematic destruction of the Armenian people and identity in the Ottoman Empire during World War I. Spearheaded by the ruling Committee of Union and Progress (CUP), it was implemented primarily through the mass murder of around one million Armenians during death marches to the Syrian Desert and the forced Islamization of others, primarily women and children.

Before World War I, Armenians occupied a somewhat protected, but subordinate, place in Ottoman society. Large-scale massacres of Armenians had occurred in the 1890s and 1909. The Ottoman Empire suffered a series of military defeats and territorial losses, especially during the 1912–1913 Balkan Wars. This sparked fear among CUP leaders that the Armenians, whose homeland in Anatolia they considered the Turkish nation's last refuge, would seek independence. During their invasion of Russian and Persian territory in 1914, Ottoman paramilitaries massacred local Armenians. Ottoman leaders took isolated instances of Armenian resistance as evidence of a widespread rebellion, and decided to permanently forestall the possibility of Armenian autonomy or independence.

Armenian Americans (Armenian: ամերիկահայեր, romanized: amerikahayer) are citizens or residents of the United States who have total or partial Armenian ancestry. They form the second largest community of the Armenian diaspora after Armenians in Russia. The first major wave of Armenian immigration to the United States took place in the late 19th and early 20th centuries. Thousands of Armenians settled in the United States following the Hamidian massacres of the mid-1890s, the Adana massacre of 1909, and the Armenian genocide of 1915–1918 in the Ottoman Empire. Since the 1950s many Armenians from the Middle East (especially from Lebanon, Syria, Iran, Iraq, Egypt, and Turkey) migrated to the United States as a result of political instability in the region. It accelerated in the late 1980s and has continued after the dissolution of the Soviet Union in 1991 due to socio-economic and political reasons. The Los Angeles area has the largest Armenian population in the United States.

The 2020 United States census reported that 519,001 Americans held full or partial Armenian roots either alone or combined with another ancestral origin. Various organizations and media criticize these numbers as an underestimate, proposing 800,000 to 1,500,000 Armenian Americans instead. The highest concentration of Americans of Armenian descent is in the Greater Los Angeles area, where 166,498 people have identified themselves as Armenian to the 2000 census, comprising over 40% of the 385,488 people who identified Armenian origins in the United States at the time. The city of Glendale, in the Los Angeles metropolitan area, is widely thought to be the center of Armenian American life (although many Armenians live in the aptly named "Little Armenia" neighborhood of Los Angeles).

Anti-Armenian sentiment, also known as anti-Armenianism and Armenophobia, encompasses a wide-ranging spectrum of hostile attitudes and expressions of negative feelings (e.g., fear, aversion, derision, suspiciousness, dislike, etc.), as well as overt racism, harmful stereotypes, and/or prejudice towards Armenians, Armenia, and Armenian culture.

Historically, anti-Armenianism has manifested itself in several ways, ranging from expressions of hatred or of discrimination against individuals of Armenian ethnic background to organized pogroms by mobs or state-sanctioned genocide. Historically, the most destructive and lethal instances of Armenophobia include the Hamidian massacres (1894–1897), the Adana massacre (1909), the Armenian genocide (1915), the Sumgait pogrom (1988), and Operation Ring (1991).