Tetrodotoxin in the context of "Neurotoxin"

Tetraodontidae is a family of marine and freshwater fish in the order Tetraodontiformes. The family includes many familiar species variously called pufferfishes, puffers, balloonfishes, blowfishes, blowers, blowies, bubblefishes, globefishes, swellfishes, toadfishes, toadies, botetes, toadle, honey toads, sugar toads, and sea squabs. They are morphologically similar to the closely related porcupinefish, which have large external spines (unlike the thinner, hidden spines of the Tetraodontidae, which are only visible when the fish have puffed up). The family name comes from Ancient Greek τετρα- (tetra-), meaning "four", and ὀδούς (odoús), meaning "tooth", referring to the four teeth of the type genus Tetraodon.

The majority of pufferfish species are toxic, with some among the most poisonous vertebrates in the world. In certain species, the internal organs, such as the liver, and sometimes the skin, contain mucus tetrodotoxin, and are highly toxic to most animals when eaten; nevertheless, the meat of some species is considered a delicacy in Japan (as 河豚, fugu), Korea (as 복, bok, or 복어, bogeo), and China (as 河豚, hétún) when prepared by specially trained chefs who know which part is safe to eat and in what quantity. Other pufferfish species with nontoxic flesh, such as the northern puffer, Sphoeroides maculatus, of the Chesapeake Bay, are considered a delicacy elsewhere.

Blue-ringed octopuses, comprising the genus Hapalochlaena, are four extremely venomous species of octopus that are found in tide pools and coral reefs in the Pacific and Indian Oceans, from Japan to Australia. They can be identified by their yellowish skin and characteristic blue and black rings that can change color dramatically when the animals are threatened. They eat small crustaceans, including crabs, hermit crabs, shrimp, and other small sea animals.

They are some of the world's most venomous marine animals. Despite their small size—12 to 20 cm (5 to 8 in)—and relatively docile nature, they are very dangerous if provoked when handled because their venom contains a powerful neurotoxin called tetrodotoxin.

Fugu (河豚; 鰒; フグ) in Japanese, bogeo (복어; 鰒魚) or bok (복) in Korean, and hétún (河豚; 河魨) in Standard Modern Chinese refers to pufferfish, normally of the genus Takifugu, Lagocephalus, or Sphoeroides, or a porcupinefish of the genus Diodon, or a dish prepared from these fish.

Fugu possesses a potentially lethal poison known as tetrodotoxin, therefore necessitating meticulous preparation to prevent the fish from being contaminated. Restaurant preparation of fugu is strictly controlled by law in Japan, Korea and several other countries, and only chefs who have qualified after three or more years of rigorous training are allowed to prepare the fish. Domestic preparation occasionally leads to accidental death.

Pseudoalteromonas tetraodonis is a marine bacterium isolated from the surface slime of the puffer fish. It secretes the neurotoxin, tetrodotoxin. It was originally described in 1990 as Alteromonas tetraodonis but was reclassified in 2001 to the genus Pseudoalteromonas.