The Ottoman persecution of Alevis is best known in connection with the Ottoman sultan Selim I's reign (1512–1520) and his war against the Safavids in 1514. But there are examples that indicate that there already existed problems with Alevi groups in the Ottoman Empire since the 14th century, The Alevis were generally persecuted for sympathizing in the negative role of Safavids.
Alevism (/æˈlɛvɪzəm/; Turkish: Alevilik; Kurdish: Elewîtî), also known as Qizilbashism, is a syncretic and mystic tradition, formulated by Haji Bektash Veli. It is generally agreed that it is akin to a Sufi rendition of Twelver Shi'ism that integrates Central Asian shamanic elements, though some dissenting voices base the Alevi belief squarely in a non-denominational, heterodox Anatolian Islam instead. They acknowledge the six articles of faith of Islam, but may differ regarding their interpretation. Lack of gender segregation in ritual contexts and clergy, is one of the key features that sets Alevism apart from Muslim orthodoxy.
Although the main order amongst Alevis, the Bektashi order, were appointed as the military chaplains until the Auspicious Incident; historical Qizilbash affiliation created political rifts which caused them to be persecuted both in Ottoman and modern Turkish regimes, being described as heterodox to contrast them with the "orthodox" Sunni majority.