Walter Bradford Cannon (October 19, 1871 – October 1, 1945) was an American physiologist, professor and chairman of the Department of Physiology at Harvard Medical School. He coined the term "fight or flight response", and developed the theory of homeostasis. He popularized his theories in his book The Wisdom of the Body, first published in 1932.
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Walter Bradford Cannon in the context of Claude Bernard
Claude Bernard (French: [klod bɛʁnaʁ]; 12 July 1813 – 10 February 1878) was a French physiologist. I. Bernard Cohen of Harvard University called Bernard "one of the greatest of all men of science". He originated the term milieu intérieur and the associated concept of homeostasis (the latter term being coined by Walter Cannon).
Walter Bradford Cannon in the context of Fight-or-flight response
The fight-or-flight or the fight-flight-freeze-or-fawn (also called hyperarousal or the acute stress response) is a physiological reaction that occurs in response to a perceived harmful event, attack, or threat to survival. It was first described by Walter Bradford Cannon in 1914 to which he referred to as "the necessities of fighting or flight" in 1915. His theory states that animals react to threats with a general discharge of the sympathetic nervous system, preparing the animal for fighting or fleeing. More specifically, the adrenal medulla produces a hormonal cascade that results in the secretion of catecholamines, especially norepinephrine and epinephrine. The hormones estrogen, testosterone, and cortisol, as well as the neurotransmitters dopamine and serotonin, also affect how organisms react to stress. The hormone osteocalcin might also play a part.
This response is recognised as the first stage of the general adaptation syndrome that regulates stress responses among vertebrates and other organisms.