Vomeronasal organ in the context of "Sex pheromone"

The dog sense of smell is the most powerful sense of this species, the olfactory system of canines being much more complex and developed than that of humans. It is believed to be up to 10 million times as sensitive as a human's in specialized breeds. Dogs have roughly forty times more smell-sensitive receptors than humans, ranging from about 125 million to nearly 300 million in some dog breeds, such as bloodhounds. These receptors are spread over an area about the size of a pocket handkerchief (compared to 5 million over an area the size of a postage stamp for humans). Dogs' sense of smell also includes the use of the vomeronasal organ, which is used primarily for social interactions.

The dog has mobile nostrils that help it determine the direction of the scent. Unlike humans, dogs do not need to fill up their lungs as they continuously bring odors into their noses in bursts of 3–7 sniffs. Dog noses have a bony structure inside that humans do not have, which allows the air that has been sniffed to pass over a bony shelf to which odor molecules adhere. The air above this shelf is not washed out when the dog breathes normally, so the scent molecules accumulate in the nasal chambers and the scent builds with intensity, allowing the dog to detect the faintest of odors and can even detect emotions.

Vestigiality is the retention, during the process of evolution, of genetically determined structures or attributes that have lost some or all of the ancestral function in a given species. Assessment of the vestigiality must generally rely on comparison with homologous features in related species. The emergence of vestigiality occurs by normal evolutionary processes, typically by loss of function of a feature that is no longer subject to positive selection pressures when it loses its value in a changing environment. The feature may be selected against more urgently when its function becomes definitively harmful, but if the lack of the feature provides no advantage, and its presence provides no disadvantage, the feature may not be phased out by natural selection and persist across species.

Examples of vestigial structures (also called degenerate, atrophied, or rudimentary organs) are the loss of functional wings in island-dwelling birds; the human vomeronasal organ; and the hindlimbs of the snake and whale.

The flehmen response (/ˈfleɪmən/; from German flehmen 'to bare the upper teeth', and Upper Saxon German flemmen 'to look spiteful'), also called the flehmen position, flehmen reaction, flehmen grimace, flehming, or flehmening, is a behavior in which an animal curls back its upper lip exposing its front teeth, inhales with the nostrils usually closed, and then often holds this position for several seconds. The behavior occurs as a response to relevant external stimuli, typically pheromones, which may have been produced by animals of the same or different species. It may be performed with the neck stretched and the head held high in the air.

Flehmen is performed by a wide range of mammals, including ungulates and felids. The behavior facilitates the transfer of pheromones and other scents into the vomeronasal organ (VNO, or Jacobson's organ) located above the roof of the mouth via a duct which exits just behind the front teeth of the animal.

The rhinarium (Neo-Latin, "belonging to the nose"; pl.: rhinaria) is the furless skin surface surrounding the external openings of the nostrils in many mammals. Commonly it is referred to as the tip of the snout, and breeders of cats and dogs sometimes use the term nose leather. Informally, it may be called a "truffle", "wet snout," or "wet nose” because its surface is moist in some species: for example, healthy dogs and cats.

In many species, the rhinarium has a mid-line groove (cleft) – the philtrum – and a wrinkled (crenellated) surface. The rhinarium is a separate sense organ: it is a touch-based chemosensory organ that connects with a well-developed vomeronasal organ (VNO). The rhinarium is used to touch a scent-marked object containing pheromones (usually large, non-volatile molecules), and transfer these pheromone molecules down the philtrum to the VNO via the nasopalatine ducts that travel through the incisive foramen of the hard palate. It also acts as a wind-direction detector: cold receptors in the skin of the rhinarium detect the orientation where evaporative cooling is highest, as determined by the wind direction.