Vittoria della Rovere in the context of Prince of the Church

The House of Della Rovere (pronounced [della ˈroːvere]; literally "of the oak tree") was a powerful Italian noble family. It had humble origins in Savona, in Liguria, and acquired power and influence through nepotism and ambitious marriages arranged by two Della Rovere popes: Francesco Della Rovere, who ruled as Sixtus IV from 1471 to 1484 and his nephew Giuliano, who became Julius II in 1503. Sixtus IV built the Sistine Chapel, which was named after him. Julius II was patron to Michelangelo, Raphael and many other Renaissance artists and started the modern rebuilt of St. Peter's Basilica. Also the Basilica of San Pietro in Vincoli in Rome was the family church of the Della Rovere. Members of the family were influential in the Church of Rome, and as dukes of Urbino, dukes of Sora and lords of Senigallia; the title of Urbino was extinguished with the death of Francesco Maria II in 1631, and the family died out with the death of his granddaughter Vittoria, Grand Duchess of Tuscany.

Ferdinando II de' Medici (14 July 1610 – 23 May 1670) was grand duke of Tuscany from 1621 to 1670. He was the eldest son of Cosimo II de' Medici and Maria Maddalena of Austria. Remembered by his contemporaries as a man of culture and science, he actively participated in the Accademia del Cimento, the first official scientific society in Italy, formed by his younger brother, Leopoldo de' Medici. His 49-year rule was punctuated by the beginning of Tuscany's long economic decline, which was further exacerbated by his successor, Cosimo III de' Medici. He married Vittoria della Rovere, a first cousin, with whom he had two children who reached adulthood: the aforementioned Cosimo III, and Francesco Maria de' Medici, Duke of Rovere and Montefeltro, a cardinal.