The Via Cassia (lit. 'Way of Cassius') was an important Roman road striking out of the Via Flaminia near the Milvian Bridge in the immediate vicinity of Rome and, passing not far from Veii, traversed Etruria. The Via Cassia passed through Baccanae, Sutrium, Volsinii, Clusium, Arretium, Florentia, Pistoria, and Luca, joining the Via Aurelia at Luna.
The Via Cassia intersected other important roads. At mile 11 the Via Clodia diverged north-north-west. At Sette Vene, another road, probably the Via Annia, branched off to Falerii. In Sutrium, the Via Ciminia split off and later rejoined.