Vardø (town) in the context of Vardøya

European route E 75 is part of the International E-road network, which is a series of main roads in Europe.

The E 75 starts at the town of Vardø in Norway by the Barents Sea, and it runs south through Finland, Poland, Czech Republic, Slovakia, Hungary, Serbia, North Macedonia, and Greece. The road ends after about 4,380 kilometres (2,720 mi) (not counting ferries) at the town of Sitia on the eastern end of the island of Crete in the Mediterranean Sea, it being the most southerly point reached by an E-road. (The northernmost one is the E69.)

Sitia (Latin and Italian) or Siteia (Greek: Σητεία, Siteía [siˈtia]) is a port town and a municipality in Lasithi, Crete, Greece. The town has 11,166 inhabitants and the municipality has 20,438 (2021). It lies east of Agios Nikolaos and northeast of Ierapetra. Sitia's port is on the Sea of Crete, part of the Aegean Sea and is one of the economic centers of the Lasithi region. European route E75 (which ends in Vardø, Norway) starts in Sitia. The town is served by the Sitia Public Airport. It has not experienced the effects of mass tourism even though there is a long beach along the road leading to Vai and several places of historical interest.