Upper Rhine (German: Oberrhein [ˈoːbɐˌʁaɪn] ; French: Rhin Supérieur is the section of the Rhine between the Middle Bridge in Basel, Switzerland, and the Rhine knee in Bingen, Germany. Representing kilometres 167 to 529 of the river it is surrounded by the Upper Rhine Plain (Oberrheinische Tiefebene). Most of its upper section marks the France–Germany border.
The Upper Rhine is one of four sections of the river between Lake Constance and the North Sea, and is succeeded downstream by the Middle Rhine and Lower Rhine; only the High Rhine and Alpine Rhine lie above it. The countries and states along the Upper Rhine are Switzerland, France (Alsace) and the German states of Baden-Württemberg, Rhineland-Palatinate and Hesse. The largest cities along the river are Basel, Mulhouse, Strasbourg, Karlsruhe, Mannheim, Ludwigshafen and Mainz.