Upper Mesopotamia in the context of "Subartu"

The Hittites (/ˈhɪtaɪts/) were an Anatolian Indo-European people who formed one of the first major civilizations of the Bronze Age in West Asia. Possibly originating from beyond the Black Sea, they settled in modern-day Turkey in the early 2nd millennium BC. The Hittites formed a series of polities in north-central Anatolia, including the kingdom of Kussara (before 1750 BC), the Kanesh or Nesha Kingdom (c. 1750–1650 BC), and an empire centered on their capital, Hattusa (around 1650 BC). Known in modern times as the Hittite Empire, it reached its peak during the mid-14th century BC under Šuppiluliuma I, when it encompassed most of Anatolia and parts of the northern Levant and Upper Mesopotamia, bordering the rival empires of the Hurri-Mitanni and Assyrians.

Between the 15th and 13th centuries BC, the Hittites were one of the dominant powers of the Near East, coming into conflict with the New Kingdom of Egypt, the Middle Assyrian Empire, and the Empire of Mitanni. By the 12th century BC, much of the Hittite Empire had been annexed by the Middle Assyrian Empire, with the remainder being sacked by Phrygian newcomers to the region. From the late 12th century BC, during the Late Bronze Age collapse, the Hittites splintered into several small independent states, some of which survived until the eighth century BC before succumbing to the Neo-Assyrian Empire; lacking a unifying continuity, their descendants scattered and ultimately merged into the modern populations of the Levant and Mesopotamia.

Nikephoros II Phokas (Greek: Νικηφόρος Φωκᾶς, romanized: Nikēphóros Phōkâs; c. 912 – 11 December 969), Latinized Nicephorus II Phocas, was Byzantine emperor from 963 to 969. His career, not uniformly successful in matters of statecraft or of war, nonetheless greatly contributed to the resurgence of the Byzantine Empire during the 10th century. In the east, Nikephoros completed the conquest of Cilicia and retook the islands of Crete and Cyprus, opening the path for subsequent Byzantine incursions reaching as far as Upper Mesopotamia and the Levant; these campaigns earned him the sobriquet "pale death of the Saracens."

The Iraqi–Syrian border is the border between Syria and Iraq and runs for a total length of 599 km (372 mi) across Upper Mesopotamia and the Syrian desert, from the tripoint with Jordan in the south-west to the tripoint with Turkey in the north-east.

Babylonia (/ˌbæbɪˈloʊniə/; Akkadian: 𒆳𒆍𒀭𒊏𒆠, māt Akkadī) was an ancient Akkadian-speaking state and cultural area based on the city of Babylon in central-southern Mesopotamia (present-day Iraq and parts of Syria). It emerged as an Akkadian-populated but Amorite-ruled state c. 1894 BC. During the reign of Hammurabi and afterwards, Babylonia was retrospectively called "the country of Akkad" (māt Akkadī in Akkadian), a deliberate archaism in reference to the previous glory of the Akkadian Empire. It was often involved in rivalry with the linguistically related state of Assyria in Upper Mesopotamia, and with Elam to the east. Babylonia briefly became the major power in the region after Hammurabi (fl. c. 1792–1752 BC middle chronology, or c. 1696–1654 BC, short chronology) created a short-lived empire, succeeding the earlier Akkadian Empire, Third Dynasty of Ur, and Old Assyrian Empire. The Babylonian Empire rapidly fell apart after the death of Hammurabi and reverted to a small kingdom centered around the city of Babylon.

Like Assyria, the Babylonian state retained the written Akkadian language for official use, despite its Northwest Semitic-speaking Amorite founders and Kassite successors, who spoke a language isolate. The state retained the Sumerian language in sacred texts for the Babylonian religion, but already by the time Babylon was founded, this was no longer a spoken language, having been replaced by Akkadian. The earlier Akkadian and Sumerian traditions played a major role in the descendant Babylonian culture, and the region would remain an important cultural center, even under its protracted periods of outside rule.

The border between the Syrian Arab Republic and the Republic of Turkey (Arabic: الحدود السورية التركية, romanized: alhudud alsuwriat alturkia; Turkish: Suriye–Türkiye sınırı) is 909 kilometres (565 mi) long, and runs from the Mediterranean Sea in the west to the tripoint with Iraq in the east. It runs across Upper Mesopotamia for some 400 kilometres (250 mi), crossing the Euphrates and reaching as far as the Tigris. Much of the border follows the Southern Turkish stretch of the Baghdad Railway, roughly along the 37th parallel between the 37th and 42nd eastern meridians. In the west, it almost surrounds the Turkish Hatay Province, partly following the course of the Orontes River and reaching the Mediterranean coast at the foot of Jebel Aqra.

The Artuqid dynasty (alternatively Artukid, Ortoqid, or Ortokid; Old Anatolian Turkish: أرتقي بيليك, Turkish: Artuklu Beyliği, Artuklular, pl. Artukoğulları) was established in 1102 as a Turkish principality of the Seljuk Empire. It formed a Turkoman dynasty rooted in the Oghuz Döğer tribe, and followed the Sunni Muslim faith. It ruled in Northern Syria and Upper Mesopotamia in the eleventh through thirteenth centuries. The Artuqid dynasty took its name from its founder, Artuk Bey, who was a member of Döger branch of the Oghuz Turks and ruled one of the Turkmen principalities of the Seljuk Empire. Artuk's sons and descendants ruled the three branches in the region: Sökmen's descendants ruled the region around Hasankeyf between 1102 and 1231; Ilghazi's branch ruled from Mardin and Mayyafariqin between 1106 and 1186 (until 1409 as vassals) and Aleppo from 1117–1128; and the Harput line starting in 1112 under the Sökmen branch, and was independent between 1185 and 1233.

Hittite (Hittite cuneiform: 𒌷𒉌𒅆𒇷, romanized: nešili, lit. 'in the language of Neša', or nešumnili lit. 'in the language of the people of Neša'), also known as Nesite (Nešite/Neshite, Nessite), is an extinct Indo-European language that was spoken by the Hittites, a people of Bronze Age Anatolia who created an empire centered on Hattusa, as well as parts of the northern Levant and Upper Mesopotamia. The language, now long extinct, is attested in cuneiform, in records dating from the 17th (Anitta text) to the 13th centuries BC, with isolated Hittite loanwords and numerous personal names appearing in an Old Assyrian context from as early as the 20th century BC, making it the earliest attested use of the Indo-European languages.

By the Late Bronze Age, Hittite had started losing ground to its close relative Luwian. It appears that Luwian was the most widely spoken language in the Hittite capital of Hattusa during the 13th century BC. After the collapse of the Hittite New Kingdom during the more general Late Bronze Age collapse, Luwian emerged in the early Iron Age as the main language of the so-called Syro-Hittite states, in southwestern Anatolia and northern Syria.

The Ayyubid dynasty (Arabic: الأيوبيون, romanized: al-Ayyūbīyūn), also known as the Ayyubid Sultanate, was the founding dynasty of the medieval Sultanate of Egypt established by Saladin in 1171, following his abolition of the Fatimid Caliphate of Egypt. A Sunni Muslim of Kurdish origin, Saladin had originally served the Zengid ruler Nur al-Din, leading the latter's army against the Crusaders in Fatimid Egypt, where he was made vizier. Following the death of his Zengid suzerain Nur al-Din in 1174, Saladin was proclaimed as the first Sultan of Egypt by the Abbasid Caliphate, and rapidly expanded the new sultanate beyond Egypt to encompass most of Syria, in addition to Hijaz, Yemen, northern Nubia, Tripolitania and Upper Mesopotamia. Saladin's military campaigns set the general borders and sphere of influence of the sultanate of Egypt for the almost 350 years of its existence. Most of the Crusader states fell to Saladin after his victory at the Battle of Hattin in 1187, but the Crusaders reconquered the Syrian coastlands in the 1190s.

After Saladin's death in 1193, his sons contested control of the sultanate, but Saladin's brother al-Adil ultimately became sultan in 1200. All of the later Ayyubid sultans of Egypt were his descendants. In the 1230s, the emirs of Syria attempted to assert their independence from Egypt and the Ayyubid realm remained divided until Sultan as-Salih Ayyub restored its unity by subduing most of Syria, except Aleppo, by 1247. By then, local Muslim dynasties had driven out the Ayyubids from Yemen, the Hejaz, and parts of Mesopotamia. After his death in 1249, as-Salih Ayyub was succeeded in Egypt by his son al-Mu'azzam Turanshah. However, the latter was soon overthrown by his Mamluk generals who had repelled a Crusader invasion of the Nile Delta. This effectively ended Ayyubid power in Egypt. Attempts by the emirs of Syria, led by an-Nasir Yusuf of Aleppo, to wrest back Egypt failed. In 1260, the Mongols sacked Aleppo and conquered the Ayyubids' remaining territories soon after. The Mamluks, who expelled the Mongols, maintained the Ayyubid principality of Hama until deposing its last ruler in 1341.