The Umayyad Caliphate or the Umayyad Empire (US: /uːˈmaɪæd/; Arabic: ٱلْخِلَافَة ٱلْأُمَوِيَّة, romanized: al-Khilāfa al-Umawiyya) was the second caliphate established after the death of the Islamic prophet Muhammad and was ruled by the Umayyad dynasty from 661 to 750. It succeeded the Rashidun Caliphate, of which the third caliph, Uthman ibn Affan, was also a member of the Umayyad clan. The Umayyad family established a dynasty with hereditary rule under Mu'awiya ibn Abi Sufyan, the long-time governor of Greater Syria, who became caliph after the end of the First Fitna in 661. After Mu'awiya's death in 680, conflicts over the succession resulted in the Second Fitna, and power was eventually claimed by Marwan ibn al-Hakam, who came from another branch of the clan. Syria remained the Umayyads' core power base thereafter, with Damascus as their capital.
The Umayyads continued the Muslim conquests, conquering Ifriqiya, Transoxiana, Sind, the Maghreb and Hispania (al-Andalus). At its greatest extent, the Umayyad Caliphate covered an area of 11,100,000 km (4,300,000 sq mi), making it one of the largest empires in history in terms of size. The dynasty was overthrown by the Abbasids in 750. Survivors of the dynasty established an emirate and then a caliphate in Córdoba, with Cordoba becoming a major center of science, medicine, philosophy and invention during the Islamic Golden Age.