Túpac Amaru II in the context of "Túpac Amaru"

A cacique, sometimes spelled as cazique (Latin American Spanish: [kaˈsike]; Portuguese: [kɐˈsikɨ, kaˈsiki]; feminine form: cacica), was a tribal chieftain of the Taíno people, who were the Indigenous inhabitants of the Bahamas, the Greater Antilles, and the northern Lesser Antilles at the time of European contact with those places. The term is a Spanish transliteration of the Taíno word kasike.

Cacique was initially translated as "king" or "prince" for the Spanish. In the colonial era, the conquistadors and the administrators who followed them used the word generically to refer to any leader of practically any indigenous group they encountered in the Western Hemisphere. In Hispanic and Lusophone countries, the term has also come to mean a political boss, similar to a caudillo, exercising power in a system of caciquism.

The Rebellion of Túpac Amaru II (4 November 1780 – 15 March 1783) was an uprising by cacique-led Aymara, Quechua, and mestizo rebels aimed at overthrowing Spanish colonial rule in Peru. The causes of the rebellion included opposition to the Bourbon Reforms, an economic downturn in colonial Peru, and a grassroots revival of Inca cultural identity led by Túpac Amaru II, an indigenous cacique and the leader of the rebellion. While Amaru II was captured and executed by the Spanish in 1781, the rebellion continued for at least another year under other rebel leaders. Amaru II's rebellion was simultaneous, and occasionally cooperated, with the uprising of Túpac Katari in colonial-era Upper Peru (now Bolivia). The rebellion was the first large-scale attempt at an independence movement in Latin America and among the largest rebellions of the 18th century.

The rebellion arose as a reaction to the imposition of the Bourbon Reforms in the Spanish viceroyalties of America and was led by the curaca José Gabriel Condorcanqui, known as Túpac Amaru II. These reforms, among others, forced the indigenous population to mine minerals under the Mit'a system. Among Túpac Amaru II's proclamations were the demands of the freedom of the indigenous population and the abolition of slavery.