Twin study in the context of "Behavior genetics"

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⭐ Core Definition: Twin study

Twin studies are studies conducted on identical or fraternal twins. They aim to reveal the importance of environmental and genetic influences for traits, phenotypes, and disorders. Twin research is considered a key tool in behavioral genetics and in related fields, from biology to psychology. Twin studies are part of the broader methodology used in behavior genetics, which uses all data that are genetically informative – siblings studies, adoption studies, pedigree, etc. These studies have been used to track traits ranging from personal behavior to the presentation of severe mental illnesses such as schizophrenia.

Twins are a valuable source for observation because they allow the study of environmental influence and varying genetic makeup: "identical" or monozygotic (MZ) twins share essentially 100% of their genes, which means that most differences between the twins (such as height, susceptibility to boredom, intelligence, depression, etc.) are due to experiences that one twin has but not the other twin. "Fraternal" or dizygotic (DZ) twins share only about 50% of their genes, the same as any other sibling. Twins also share many aspects of their environment (e.g., uterine environment, parenting style, education, wealth, culture, community) because they are born into the same family. The presence of a given genetic or phenotypic trait in only one member of a pair of identical twins (called discordance) provides a powerful window into environmental effects on such a trait.

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Twin study in the context of Nazi human experimentation

Nazi human experimentation was a series of medical experiments on prisoners by Nazi Germany in its concentration camps mainly between 1942 and 1945. There were 15,754 documented victims, of various nationalities and ages, although the true number is believed to be more. About a quarter of documented victims were killed and survivors generally experienced severe permanent injuries.

At Auschwitz and other camps, under the direction of Eduard Wirths, selected inmates were subjected to various experiments that were designed to help German military personnel in combat situations, develop new weapons, aid in the recovery of military personnel who had been injured, and to advance Nazi racial ideology and eugenics, including the twin experiments of Josef Mengele. Aribert Heim conducted similar medical experiments at Mauthausen.

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