Syracuse (/ˈsɪrəkjuːz, ˈsɛr-, -kjuːs/ SIRR-ə-kewz, SERR-, -kewss) is a city in New York, United States, and the county seat of Onondaga County. With a population of 148,620 and a metropolitan area of 662,057, it is the fifth-most populated city and 13th-most populated municipality in the state of New York.
Formally established in 1820, Syracuse was named after the classical Greek city of Syracuse (Siracusa in Italian), located on the eastern coast of the Italian island of Sicily, for its similar natural features. Adjacent brine springs made the city a major producer of commercial salt into the late 19th century, earning the nickname "The Salt City"; it subsequently became a major industrial center until the mid-20th century, and has since been a hub for higher education, research, and services.