The St. Marys River, sometimes written St. Mary's River, drains Lake Superior, starting at the end of Whitefish Bay and flowing 74.5 miles (119.9 km) southeast into Lake Huron, with a fall of 23 feet (7.0 m). For its entire length it is an international border, separating Michigan in the United States from Ontario, Canada.
The twin cities of Sault Ste. Marie, Ontario, and Sault Ste. Marie, Michigan, are connected across the St. Marys River by the Sault Ste. Marie International Bridge. The St. Marys Rapids are just below the river's exit from Lake Superior and can be bypassed by huge freight ships through the man-made Soo Locks and the Sault Ste. Marie Canal.