Spinola Palace (Maltese: Palazz ta' Spinola; Italian: Palazzo Spinola), also known as Spinola House and Villa Spinola, is a palace in St. Julian's, Malta. It was built in the 17th century by Fra Paolo Rafel Spinola, a knight of the Order of St. John, and was enlarged in the 18th century. The later construction was designed by Romano Carapecchia, which is considered a masterpiece, with its back having an elegant clock that is a unique feature to secular Baroque architecture in Malta.
The palace was adaptively converted to a military hospital, serving between 1860 and 1922, and was known as the Forrest Hospital. It later served for a number of purposes, including a post-World War II shelter for the homeless, a short-lived Museum of Modern Art and the Ministry for Tourism office. From late 2007 till 2021, the building hosted the Headquarters of the Parliamentary Assembly of the Mediterranean (PAM).