Indigenous people lived in what is now Texas more than 10,000 years ago, as evidenced by the discovery of the remains of prehistoric Leanderthal Lady. In 1519, the arrival of the first Spanish conquistadors in the region of North America now known as Texas found the region occupied by numerous Native American tribes. The name Texas derives from táyshaʼ, a word in the Caddoan language of the Hasinai, which means "friends" or "allies." In the recorded history of what is now the U.S. state of Texas, all or parts of Texas have been claimed by six countries: France, Spain, Mexico, the Republic of Texas, the Confederacy during the Civil War, and the United States of America.
The first European settlement was established in 1681, along the upper Rio Grande river, near modern El Paso. The settlers were exiled Spaniards and Native Americans from the Pueblo of Isleta after the Pueblo Revolt, from Santa Fe de Nuevo México (the northern part of present-day New Mexico). In 1685, Robert de La Salle (1643–1687), established a French colony at Fort Saint Louis, after sailing down and exploring the Mississippi River from New France (modern Canada) and the Great Lakes. He planted this early French presence at Fort Saint Louis near Matagorda Bay, along the Gulf of Mexico coast (near modern Inez, Texas), even before the establishment of New Orleans. The colony was killed off by Native Americans after three years, but Spanish authorities felt pressed to establish settlements to keep their claim to the land. Several Roman Catholic missions were established in East Texas; they were abandoned in 1691. Twenty years later, concerned with the continued French presence in neighboring Louisiana, Spanish authorities again tried to colonize Texas. Over the next 110 years, Spain established numerous villages, presidios, and missions in the province. A small number of Spanish settlers arrived, in addition to missionaries and soldiers. Spain signed agreements with colonists from the United States, bordering the province to the northeast ever since their Louisiana Purchase from the Emperor Napoleon I and his French Empire (France) in 1803. When Mexico won its independence from Spain in 1821, Mexican Texas was part of the new nation. To encourage settlement, Mexican authorities allowed organized immigration from the United States, and by 1834, over 30,000 Anglos lived in Texas, compared to 7,800 Mexicans.