Skanderbeg's rebellion (Albanian: Kryengritja e Skënderbeut) was an almost 25-year long anti-Ottoman rebellion led by the Albanian military commander Skanderbeg in what is today Albania and North Macedonia. It was a rare successful instance of resistance by Christians during the 15th century and through his leadership led Albanians in guerrilla warfare against the Ottomans.
On 2 March 1444, the regional Albanian chieftains and nobles united against the Ottoman Empire and established the League of Lezhë. The coalition would go on to successfully fight the Ottoman forces up until the fall of Shkodër in 1479, after which it was dissolved. After Skanderbeg's death in 1468, the league would continue fighting under Lekë Dukagjini.