The Shire of Southern Grampians is a local government area (LGA) in the Barwon South West region of Victoria, Australia, located in the south-western part of the state. It covers an area of 6,654 square kilometres (2,569 mi) and in June 2018 had a population of 16,135. It includes the city of Hamilton and the towns of Coleraine, Dunkeld and Penshurst.
The Shire is governed and administered by the Southern Grampians Shire Council; its seat of local government and administrative centre is located at the council headquarters in Hamilton, it also has service centres located in a couple of other locations within Hamilton. The Shire is named after the major geographical feature in the region, The Grampians, and that the southern part of this feature occupies the northern part of the LGA.