Anoplotherium is the type genus of the extinct Palaeogene artiodactyl family Anoplotheriidae, which was endemic to Western Europe. It lived from the Late Eocene to the earliest Oligocene. It was the fifth fossil mammal genus to be described with official taxonomic authority, with a history extending back to 1804 when its fossils from Montmartre in Paris, France were first described by the French naturalist Georges Cuvier. Discoveries of incomplete skeletons of A. commune in 1807 led Cuvier to thoroughly describe unusual features for which there are no modern analogues. His drawn skeletal and muscle reconstructions of A. commune in 1812 were amongst the first instances of anatomical reconstructions based on fossil evidence. Cuvier's contributions to palaeontology based on his works on the genus were revolutionary for the field, not only proving the developing ideas of extinction and ecological succession but also paving the way for subfields such as palaeoneurology. Today, there are four known species.
Anoplotherium was amongst the largest non-whippomorph artiodactyls of the Palaeogene period, weighing on average 115 kg (254 lb) to 271 kg (597 lb) and measuring at least 2.5 m (8 ft 2 in) in head and body length and 1.25 m (4 ft 1 in) in shoulder height. It was an evolutionarily advanced and unusual artiodactyl, sporting three-toed feet in certain species like A. latipes, a long and robust tail, and a highly-developed brain with strong support for both sense of smell and sensory perception. Its overall robust build and elongate tail has been suggested to have allowed it to stand bipedally like a gerenuk to browse on plants at greater heights, reaching approximately 3 m (9.8 ft) tall, effectively competing with the few other medium to large herbivores it lived with. The full extent of its bipedalism needs to be confirmed by more research, however. The larger, two-toed A. commune and slightly smaller, three-toed A. latipes may be sexual dimorphs in that the former is female and the latter male, but this idea remains speculative. Its closest relative was Diplobune, which similarly is hypothesized to have had specialized behaviours.
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