The German mediatisation (; German: deutsche Mediatisierung) was the major redistribution and reshaping of territorial holdings that took place between 1802 and 1814 in Germany by means of the subsumption and secularisation of a large number of Imperial Estates. Nearly all the ecclesiastical principalities and free imperial cities, as well as most minor secular principalities and other self-ruling entities of the Holy Roman Empire lost their independent status and were absorbed by the remaining states. By the end of the mediatisation process, the number of German states had been reduced from almost 300 to 39.
In the strict sense of the word, mediatisation consists in the subsumption of an immediate (unmittelbar) state into another state, thus becoming mediate (mittelbar), while generally leaving the dispossessed ruler with his private estates and a number of privileges and feudal rights, such as low justice. For convenience, historians use the term mediatisation for the entire restructuring process that took place at the time, whether the mediatised states persisted in some form or lost all individuality. The secularisation of ecclesiastical states took place concurrently with the mediatisation of free imperial cities and other secular states.