The Church of Saint Alphonus of Liguori (Chiesa di Sant'Alfonso di Liguori all'Esquilino in Italian) is a rectory church located on the Via Merulana on the Esquiline Hill of central Rome's Vth prefecture, Italy, and a titular church for a Cardinal-priest under the name Santissimo Redentore e Sant'Alfonso in Via Merulana (Church of the Most Holy Redeemer and Saint Alphonse).
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Sant'Alfonso di Liguori in the context of Our Lady of Perpetual Help
Our Mother of Perpetual Succour (Latin: Nostra Mater de Perpetuo Succursu), colloquially known as Our Lady of Perpetual Help), is a Catholic title of the Blessed Virgin Mary associated with a 15th-century Byzantine icon and a purported Marian apparition. The image was enshrined in the Church of San Matteo in Via Merulana from 1499 to 1798 and is today permanently enshrined in the Church of Saint Alphonsus of Liguori in Rome, where the novena to Our Mother of Perpetual Help is prayed weekly.
Pope Pius IX granted a pontifical decree of canonical coronation along with its official formalized title Nostra Mater de Perpetuo Succursu on 5 May 1866. The Latin Patriarch of Constantinople, Cardinal Ruggero Luigi Emidio Antici Mattei, executed the rite of coronation on 23 June 1867.