Sakastan in the context of "Zabol"

Mithridates II (also spelled Mithradates II or Mihrdad II; Parthian: 𐭌𐭄𐭓𐭃𐭕 Mihrdāt) was king of the Parthian Empire from 124 to 91 BC. Considered one of the greatest of his dynasty to ever rule, he was known as Mithridates the Great in antiquity.

Mithridates II was crowned king after the abrupt death of his predecessor Artabanus I. Inheriting a declining empire that was reeling from military pressure in both the east and west, Mithridates II quickly stabilized the situation in Mesopotamia by gaining the allegiance of Characene, and subduing the insurgent Kingdom of Elymais and also the Arabs, who had continuously raided Babylonia. Mithridates II was the first Parthian king to extend Parthian rule into the Caucasus, where the kingdoms of Armenia, Iberia, and possibly Caucasian Albania became Parthian vassal states. To the east, he defeated and conquered the nomadic tribes in Bactria who had killed both of his predecessors. Sakastan was also reconquered, which was given as a fiefdom to the House of Suren. In 114/113 BC, he seized Dura-Europos in Syria from the Seleucids, and by 95 BC, the northern Mesopotamian kingdoms of Adiabene, Gordyene, and Osrhoene had acknowledged his authority. Under Mithridates II, the Parthian Empire reached it's zenith and extended from Syria and the Caucasus to Central Asia and India. It was under Mithridates II that the Parthian Empire for the first time established diplomatic relations with Rome and Han China.

The Indo-Parthian kingdom, also known as Pahlavas or Pahlawas in ancient Sanskrit texts. was a Parthian kingdom founded by Gondophares in the Indus Valley (modern-day Pakistan) and was active from 19 CE to c. 226 CE. At their zenith, they ruled an area covering parts of eastern Iran, various parts of Afghanistan and the northwest regions of the Indian subcontinent (most of modern Pakistan and parts of northwestern India). The rulers may have been members of the House of Suren, and the kingdom has even been called the "Suren Kingdom" by some authors.

The kingdom was founded in 19/20 when the governor of Drangiana (Sakastan) Gondophares declared independence from the Parthian Empire. He would later make expeditions to the east, conquering territory from the Indo-Scythians and Indo-Greeks, thus transforming his kingdom into an empire. The domains of the Indo-Parthians were greatly reduced following the invasions of the Kushans in the second half of the 1st. century. They managed to retain control of Sakastan, until its conquest by the Sasanian Empire in c. 224/5. In Baluchistan, the Paratarajas, a local Indo-Parthian dynasty, fell into the orbit of the Sasanian Empire circa 262 CE.