Saint Paul, Antigua and Barbuda in the context of Saint Mary, Antigua and Barbuda

Saint John (Antiguan and Barbudan Creole: Sen Jaan), officially the Parish of Saint John, is a civil parish of Antigua and Barbuda, on the northwestern portion of Antigua island. Its capital is the city of St. John's. Saint John borders Saint Mary, Saint Peter, Saint George, and Saint Paul. Saint John faces the Caribbean Sea. Saint John is surrounded by some of Antigua's most premier beaches. Saint John had a population of 56,736 in a 2018 estimate, making it home to the majority of the population in Antigua and Barbuda.

While Saint John is a civil administrative division, the Anglican parish church is located in the city of St. John's. Saint John is mostly centered around the St. John's urban area and the northern tourist area, but is also home to more rural areas in the southern salient and in the Five Islands-Yeptons area. Due to Saint John holding the majority of the population of Antigua and Barbuda, it is home to hundreds of populated locations some of which are vastly different from another. The island of Redonda is also under the administration of Saint John.

Saint Mary (South Antiguan Creole: Sen Mieree), officially the Parish of Saint Mary, is a parish of Antigua and Barbuda on the island of Antigua. Saint Mary borders Saint John to the north, and Saint Paul to the east. Saint Mary is dominated by the Shekerley Mountains, and its northern border is largely defined by the mountains, and by Cooks Creek. The largest city in the parish is Bolans, home to the Jolly Harbour neighbourhood, and the parish church is located in Old Road. Saint Mary was permanently established with the other four original parishes in 1692. It had an estimated population of 8,141 in 2018.

The only area in which the Antigua black pineapple can be produced is the Pineapple Belt, which includes Saint Mary. The settlements of Old Road and Urlings are located in the southern part of the parish, and Bolans and Jennings are located in the flat northern half of the parish, where the majority of Saint Mary's population is concentrated. The Shekerley Mountains shield most of the parish's land area from human population, leaving the remaining portion of the parish largely uninhabited. The remote community of John Hughes, which has less ties to the parish as a whole than to Swetes in Saint Paul, is one of the few settlements found inside the Sherkerley Mountains.

Saint Peter (Antiguan and Barbudan Creole: Sen Peeta), officially the Parish of Saint Peter, is a parish of Antigua and Barbuda on the island of Antigua. Saint Peter borders Saint Paul to the south, Saint Philip to the east, and Saint George and Saint John to the west. Saint Peter is dominated by farmland, savanna, and undeveloped fields, and its borders are not well-defined. The largest city fully within the parish is Parham, which is also the capital. However, the portion of the city of All Saints in Saint Peter is significantly larger than Parham. Saint Peter was created with the other four original parishes in 1692. It had an estimated population of 5,706 in 2018.

Saint Peter is mostly dominated by agriculture and industry, with the few populated places in the parish being portions of All Saints, Diamonds, Freemans, Pares, Parham, and Vernons. Most of the parish lives on the western border with Saint John. Pares is the only major settlement in the center of the parish. There is almost no settlement in the eastern portion of the parish other than the hamlets of Coconut Hall and Gilberts. In the northern areas of the parish, Saint Peter is home to Guiana Island and the North Sound Islands, as well as the Crabbs Peninsula. Long Island, home to three permanent inhabitants, and Maiden Island are legally part of Saint George, but are politically and statistically part of Saint Peter. Long Island and Maiden Island are counted as parts of Saint Peter for purposes of the census.