Pope Clement VII in the context of "Thomas Cromwell"

The English Reformation began in 16th-century England when the Church of England broke away first from the authority of the pope and bishops over the King and then from some doctrines and practices of the Catholic Church. These events were part of the wider European Reformation: various religious and political movements that affected both the practice of Christianity in Western and Central Europe and relations between church and state.

The English Reformation began as more of a political affair than a theological dispute. In 1527 Henry VIII sought an annulment of his marriage, but Pope Clement VII refused. In response, the Reformation Parliament (1529–1536) passed laws abolishing papal authority in England and declared Henry to be head of the Church of England. Final authority in doctrinal disputes now rested with the monarch. Though a religious traditionalist himself, Henry relied on Protestants to support and implement his religious agenda.

Henry VIII (28 June 1491 – 28 January 1547) was King of England from 22 April 1509 until his death in 1547. Henry was a dominant and forceful monarch. He is also known for his six marriages and his efforts to have his first marriage, to Catherine of Aragon, annulled. His disagreement with Pope Clement VII about such an annulment led Henry to initiate the English Reformation, separating the Church of England from papal authority. He appointed himself Supreme Head of the Church of England and dissolved convents and monasteries, for which he was excommunicated by the pope.

Born in Greenwich, Henry brought radical changes to the Constitution of England, expanding royal power and ushering in the theory of the divine right of kings in opposition to papal supremacy. He frequently used charges of treason and heresy to quell dissent, and those accused were often executed without a formal trial using bills of attainder. He achieved many of his political aims through his chief ministers, some of whom were banished or executed when they fell out of his favour. Thomas Wolsey, Thomas More, Thomas Cromwell, and Thomas Cranmer all figured prominently in his administration.

The Sack of Rome, then part of the Papal States, followed the capture of Rome on 6 May 1527 by the mutinous troops of Charles V, Holy Roman Emperor, during the War of the League of Cognac. Charles V only intended to threaten military action to make Pope Clement VII come to his terms. However, most of the Imperial army (14,000 Germans, including Lutherans, 6,000 Spaniards and some Italians) were largely unpaid. Despite being ordered not to storm Rome, they broke into the scarcely defended city and began looting, killing, and holding citizens for ransom without any restraint. Clement VII took refuge in Castel Sant'Angelo after the Swiss Guard were annihilated in a delaying rear guard action; he remained there until a ransom was paid to the pillagers.

Benvenuto Cellini, eyewitness to the events, described the sack in his works. It was not until February 1528 that the spread of a plague and the approach of the League forces under Marshal of France Odet de Foix forced the army to withdraw towards Naples from the city. Rome's population had dropped from 55,000 to 10,000 due to the atrocities, famine, an outbreak of plague, and flight from the city. The subsequent loss of the League army during the Siege of Naples secured a victory in the War of the League of Cognac for Charles V. The Emperor denied responsibility for the sack and came to terms again with Clement VII. On the other hand, the Sack of Rome further exacerbated religious hatred and antagonism between Catholics and Lutherans.

The Last Judgment (Italian: Il Giudizio Universale) is a fresco by the Italian Renaissance painter Michelangelo covering the whole altar wall of the Sistine Chapel in Vatican City. It is a depiction of the Second Coming of Christ and the final and eternal judgment by God of all humanity. The dead rise and descend to their fates, as judged by Christ who is surrounded by prominent saints. Altogether there are over 300 figures, with nearly all the males and angels originally shown as nudes; many were later partly covered up by painted draperies, of which some remain after recent cleaning and restoration.

The work took over four years to complete between 1536 and 1541 (preparation of the altar wall began in 1535). Michelangelo began working on it 25 years after finishing the Sistine Chapel ceiling, and was nearly 67 at its completion. He had originally accepted the commission from Pope Clement VII, but it was completed under Pope Paul III whose stronger reforming views probably affected the final treatment.

The House of Medici (English: /ˈmɛdɪtʃi/ MED-itch-ee, UK also /məˈdiːtʃi/ mə-DEE-chee; Italian: [ˈmɛːditʃi]) was an Italian banking family and political dynasty that first consolidated power in the Republic of Florence under Cosimo de' Medici and his grandson Lorenzo "the Magnificent" during the first half of the 15th century. The family originated in the Mugello region of Tuscany, and prospered gradually in trade until it was able to fund the Medici Bank. This bank was the largest in Europe in the 15th century and facilitated the Medicis' rise to political power in Florence, although they officially remained citizens rather than monarchs until the 16th century.

In 1532, the family acquired the hereditary title Duke of Florence. In 1569, the duchy was elevated to the Grand Duchy of Tuscany after territorial expansion. The Medici ruled the Grand Duchy from its inception under the builder Cosimo I until 1737, with the death of Gian Gastone de' Medici. The Medici produced four popes of the Catholic Church—Pope Leo X (1513–1521), Pope Clement VII (1523–1534), Pope Pius IV (1559–1565) and Pope Leo XI (1605)—and two queens of France—Catherine de' Medici (1547–1559) and Marie de' Medici (1600–1610). The Medici's grand duchy witnessed degrees of economic growth under the early grand dukes, but was bankrupt by the time of Cosimo III de' Medici (r. 1670–1723).

The Duchy of Florence (Italian: Ducato di Firenze) was an Italian principality that was centred on the city of Florence, in Tuscany, Italy. The duchy was founded after Pope Clement VII, himself a Medici, appointed his relative Alessandro de' Medici as Duke of the Florentine Republic, thereby transforming the Republic of Florence into a hereditary monarchy.

The second Duke, Cosimo I, established a strong Florentine navy and expanded his territory, purchasing Elba and conquering Siena. In 1569, Pope Pius V declared Cosimo Grand Duke of Tuscany. The Medici ruled the Grand Duchy of Tuscany until 1737.

The War of the League of Cognac (1526–1530) was fought between the Habsburg dominions of Charles V—primarily the Holy Roman Empire and Spain—and the League of Cognac, an alliance including the Kingdom of France, Pope Clement VII, the Republic of Venice, the Kingdom of England, the Duchy of Milan, and the Republic of Florence.