Parasitism in the context of Evolutionary arms race

Helminthiasis, also known as worm infection, is any macroparasitic disease of humans and other animals in which a part of the body is infected with parasitic worms, known as helminths. There are numerous species of these parasites, which are broadly classified into tapeworms, flukes, and roundworms. They often live in the gastrointestinal tract of their hosts, but they may also burrow into other organs, where they induce physiological damage.

Soil-transmitted helminthiasis and schistosomiasis are the most important helminthiases, and are among the neglected tropical diseases. These group of helminthiases have been targeted under the joint action of the world's leading pharmaceutical companies and non-governmental organizations through a project launched in 2012 called the London Declaration on Neglected Tropical Diseases, which aimed to control or eradicate certain neglected tropical diseases by 2020.

Schistosomiasis, also known as snail fever, bilharzia, and Katayama fever is a neglected tropical disease caused by parasitic flatworms called schistosomes. It affects both humans and animals. It affects the urinary tract or the intestines. Symptoms include abdominal pain, diarrhea, bloody stool, or blood in the urine. Those who have been infected for a long time may experience liver damage, kidney failure, infertility, or bladder cancer. In children, schistosomiasis may cause poor growth and learning difficulties. Schistosomiasis belongs to the group of helminth infections.

Schistosomiasis is spread by contact with fresh water contaminated with parasites released from infected freshwater snails. Diagnosis is made by finding the parasite's eggs in a person's urine or stool. It can also be confirmed by finding antibodies against the disease in the blood.

In ecology, habitat refers to the array of resources, biotic factors that are present in an area, such as to support the survival and reproduction of a particular species. A species' habitat can be seen as the physical manifestation of its ecological niche. Thus "habitat" is a species-specific term, fundamentally different from concepts such as environment or vegetation assemblages, for which the term "habitat-type" is more appropriate.

The physical factors may include (for example): soil, moisture, range of temperature, and light intensity. Biotic factors include the availability of food and the presence or absence of predators. Every species has particular habitat requirements, habitat generalist species are able to thrive in a wide array of environmental conditions while habitat specialist species require a very limited set of factors to survive. The habitat of a species is not necessarily found in a geographical area, it can be the interior of a stem, a rotten log, a rock or a clump of moss; a parasitic organism has as its habitat the body of its host, part of the host's body (such as the digestive tract), or a single cell within the host's body.

Mites are small arachnids (eight-legged arthropods) of two large orders, the Acariformes and the Parasitiformes, which were historically grouped together in the subclass Acari. However, most recent genetic analyses do not recover the two as each other's closest relative within Arachnida, rendering the group invalid as a clade. Most mites are tiny, less than 1 mm (0.04 in) in length, and have a simple, unsegmented body plan. The small size of most species makes them easily overlooked; some species live in water, many live in soil as decomposers, others live on plants, sometimes creating galls, while others are predators or parasites. This last type includes the commercially destructive Varroa parasite of honey bees, as well as scabies mites of humans. Most species are harmless to humans, but a few are associated with allergies or may transmit diseases.

The scientific discipline devoted to the study of mites is called acarology.

The nematodes (/ˈnɛmətoʊdz/ NEM-ə-tohdz or NEEM-; Ancient Greek: Νηματώδη; Latin: Nematoda), roundworms or eelworms constitute the phylum Nematoda. Species in the phylum inhabit a broad range of environments. Most species are free-living, feeding on microorganisms, but many are parasitic. Parasitic worms (helminths) are the cause of soil-transmitted helminthiases.

They are classified along with arthropods, tardigrades and other moulting animals in the clade Ecdysozoa. Unlike the flatworms, nematodes have a tubular digestive system, with openings at both ends. Like tardigrades, they have a reduced number of Hox genes, but their sister phylum Nematomorpha has kept the ancestral protostome Hox genotype, which shows that the reduction has occurred within the nematode phylum.

Yersinia pestis (Y. pestis; formerly Pasteurella pestis) is a gram-negative, non-motile, coccobacillus bacterium without spores. It is related to pathogens Yersinia enterocolitica, and Yersinia pseudotuberculosis, from which it evolved. Yersinia pestis is responsible for the disease plague, which caused the Plague of Justinian and the Black Death, one of the deadliest pandemics in recorded history. Plague takes three main forms: pneumonic, septicemic, and bubonic. Y. pestis is a facultative anaerobic parasitic bacterium that can infect humans primarily via its host the Oriental rat flea (Xenopsylla cheopis), but also through aerosols and airborne droplets for its pneumonic form. As a parasite of its host, the rat flea, which is also a parasite of rats, Y. pestis is a hyperparasite.

Y. pestis was discovered in 1894 by Alexandre Yersin, a Swiss/French physician and bacteriologist from the Pasteur Institute, during an epidemic of the plague in Hong Kong. Yersin was a member of the Pasteur school of thought. Kitasato Shibasaburō, a Japanese bacteriologist who practised Koch's methodology, was also engaged at the time in finding the causative agent of the plague. However, Yersin actually linked plague with a bacillus, initially named Pasteurella pestis; it was renamed Yersinia pestis in 1944.

The germ theory of disease is the currently accepted scientific theory for many diseases. It states that microorganisms known as pathogens or "germs" can cause disease. These small organisms, which are too small to be seen without magnification, invade animals, plants, and even bacteria. Their growth and reproduction within their hosts can cause disease. "Germ" refers not just to bacteria but to any type of microorganism, such as protists or fungi, or other pathogens, including parasites, viruses, prions, or viroids. Diseases caused by pathogens are called infectious diseases. Even when a pathogen is the principal cause of a disease, environmental and hereditary factors often influence the severity of the disease, and whether a potential host individual becomes infected when exposed to the pathogen. Pathogens are disease-causing agents that can pass from one individual to another, across multiple domains of life.

Basic forms of germ theory were proposed by Girolamo Fracastoro in 1546, and expanded upon by Marcus von Plenciz in 1762. However, such views were held in disdain in Europe, where Galen's miasma theory remained dominant among scientists and doctors.

Slime molds or slime moulds are a variety of small or microscopic organisms in different groups. They have both single-celled and multicellular forms during their life cycle, the individual cells coming together to form fruiting bodies that produce spores. Most live in damp places such as rotting wood.

More formally, the slime molds are a polyphyletic assemblage of distantly related eukaryotic organisms in the Stramenopiles, Rhizaria, Discoba, Amoebozoa and Holomycota clades. Most are near-microscopic; those in the Myxogastria form larger plasmodial slime molds visible to the naked eye. Spores are often produced in macroscopic multicellular or multinucleate fruiting bodies formed through aggregation or fusion; aggregation is driven by chemical signals called acrasins. Slime molds contribute to the decomposition of dead vegetation; some are parasitic.

Symbiosis is any close and long-term biological interaction between two organisms of different species. In 1879, Heinrich Anton de Bary defined symbiosis as "the living together of unlike organisms". The term is sometimes more exclusively used in a restricted, mutualistic sense, where both symbionts contribute to each other's subsistence. This means that they benefit each other in some way.

Symbiosis is diverse and can be classified in multiple ways. It can be obligate, meaning that one or both of the organisms depend on each other for survival, or facultative, meaning that they can subsist independently. When one organism lives on the surface of another, such as head lice on humans, it is called ectosymbiosis; when one partner lives inside the tissues of another, such as Symbiodinium within coral, it is termed endosymbiosis. Where the interaction reduces both parties' fitness, it is called competition; where just one party's fitness is reduced, it is called amensalism. Where one benefits but the other is largely unaffected, this is termed commensalism. Where one benefits at the other's expense, it is called parasitism. Finally, where both parties benefit, the relationship is described as mutualistic.

Predation is a biological interaction in which one organism, the predator, kills and eats another organism, its prey. It is one of a family of common feeding behaviours that includes parasitism and micropredation (which usually do not kill the host) and parasitoidism (which always does, eventually). It is distinct from scavenging on dead prey, though many predators also scavenge; it overlaps with herbivory, as seed predators and destructive frugivores are predators.

Predation behaviour varies significantly depending on the organism. Many predators, especially carnivores, have evolved distinct hunting strategies. Pursuit predation involves the active search for and pursuit of prey, whilst ambush predators instead wait for prey to present an opportunity for capture, and often use stealth or aggressive mimicry. Other predators are opportunistic or omnivorous and only practice predation occasionally.

Protozoa (sg.: protozoan or protozoon; alternative plural: protozoans) are a polyphyletic group of single-celled eukaryotes, either free-living or parasitic, that feed on organic matter such as other microorganisms or organic debris. Historically, protozoans were regarded as "one-celled animals".

When first introduced by Georg Goldfuss, in 1818, the taxon Protozoa was erected as a class within the Animalia, with the word 'protozoa' meaning "first animals", because they often possess animal-like behaviours, such as motility and predation, and lack a cell wall, as found in plants and many algae.

Anopheles (/əˈnɒfɪliːz/) is a genus of mosquito first described by the German entomologist J. W. Meigen in 1818, and are known as nail mosquitoes and marsh mosquitoes. Many such mosquitoes are vectors of the parasite Plasmodium, a genus of protozoans that cause malaria in birds, reptiles, and mammals, including humans. The Anopheles gambiae mosquito is the best-known species of marsh mosquito that transmits the Plasmodium falciparum, which is a malarial parasite deadly to human beings; no other mosquito genus is a vector of human malaria.

The genus Anopheles diverged from other mosquitoes approximately 100 million years ago (mya), and, like other mosquitoes, the eggs, larvae, and pupae are aquatic. The Anopheles larva has no respiratory siphon through which to breathe, so it breathes and feeds with its body horizontal to the surface of the water. The adult mosquito hatches from the surface and feeds on the nectar of flowers; the female mosquito also feeds on blood, which animal diet allows them to carry and transmit parasites between hosts. The adult's feeding position is head-down, unlike the horizontal stance of the culicines. Anopheles are distributed almost worldwide, throughout the tropics, the subtropics, and the temperate regions of planet Earth. In hot weather, adult Anopheles aestivate, which is a state of dormancy that enables the mosquito to survive in hot dry regions, such as the Sahel.

A mycorrhizal network (also known as a common mycorrhizal network or CMN) is an underground network found in forests and other plant communities, created by the hyphae of mycorrhizal fungi joining with plant roots. This network connects individual plants together. Mycorrhizal relationships are most commonly mutualistic, with both partners benefiting, but can be commensal or parasitic, and a single partnership may change between any of the three types of symbiosis at different times. Mycorrhizal networks were discovered in 1997 by Suzanne Simard, professor of forest ecology at the University of British Columbia in Canada. Simard grew up in Canadian forests where her family had made a living as foresters for generations. Her field studies revealed that trees are linked to neighboring trees by an underground network of fungi that resembles the neural networks in the brain. In one study, Simard watched as a Douglas fir that had been injured by insects appeared to send chemical warning signals to a ponderosa pine growing nearby. The pine tree then produced defense enzymes to protect against the insect.

The formation and nature of these networks is context-dependent, and can be influenced by factors such as soil fertility, resource availability, host or mycosymbiont genotype, disturbance and seasonal variation. Some plant species, such as buckhorn plantain, a common lawn and agricultural weed, benefit from mycorrhizal relationships in conditions of low soil fertility, but are harmed in higher soil fertility. Both plants and fungi associate with multiple symbiotic partners at once, and both plants and fungi are capable of preferentially allocating resources to one partner over another.

The immune system is a network of biological systems that protects an organism from diseases. It detects and responds to a wide variety of pathogens, such as viruses, bacteria, and parasites, as well as cancer cells and objects, such as wood splinters—distinguishing them from the organism's own healthy tissue. Many species have two major subsystems of the immune system. The innate immune system provides a preconfigured response to broad groups of situations and stimuli. The adaptive immune system provides a tailored response to each stimulus by learning to recognize molecules it has previously encountered. Both use molecules and cells to perform their functions.

Nearly all organisms have some kind of immune system. Bacteria have a rudimentary immune system in the form of enzymes that protect against viral infections. Other basic immune mechanisms evolved in ancient plants and animals and remain in their modern descendants. These mechanisms include phagocytosis, antimicrobial peptides called defensins, and the complement system. Jawed vertebrates, including humans, have even more sophisticated defense mechanisms, including the ability to adapt to recognize pathogens more efficiently. Adaptive (or acquired) immunity creates an immunological memory leading to an enhanced response to subsequent encounters with that same pathogen. This process of acquired immunity is the basis of vaccination.

A food web is the natural interconnection of food chains and a graphical representation of what-eats-what in an ecological community. Position in the food web, or trophic level, is used in ecology to broadly classify organisms as autotrophs or heterotrophs. This is a non-binary classification; some organisms (such as carnivorous plants) occupy the role of mixotrophs, or autotrophs that additionally obtain organic matter from non-atmospheric sources.

The linkages in a food web illustrate the feeding pathways, such as where heterotrophs obtain organic matter by feeding on autotrophs and other heterotrophs. The food web is a simplified illustration of the various methods of feeding that link an ecosystem into a unified system of exchange. There are different kinds of consumer–resource interactions that can be roughly divided into herbivory, carnivory, scavenging, and parasitism. Some of the organic matter eaten by heterotrophs, such as sugars, provides energy. Autotrophs and heterotrophs come in all sizes, from microscopic to many tonnes - from cyanobacteria to giant redwoods, and from viruses and bdellovibrio to blue whales.

Copepods (/ˈkoʊpəpɒd/; meaning 'oar-feet') are a group of small crustaceans found in nearly every freshwater and saltwater habitat. Some species are planktonic (living in the water column), some are benthic (living on the sediments), several species have parasitic phases, and some continental species may live in limnoterrestrial habitats and other wet terrestrial places, such as swamps, under leaf fall in wet forests, bogs, springs, ephemeral ponds, puddles, damp moss, or water-filled recesses of plants (phytotelmata) such as bromeliads and pitcher plants. Many live underground in marine and freshwater caves, sinkholes, or stream beds. Copepods are sometimes used as biodiversity indicators.

Mosquitoes, the Culicidae, are a family of small flies consisting of 3,600 species. The word mosquito (formed by mosca and diminutive -ito) is Spanish and Portuguese for little fly. Mosquitoes have a slender segmented body, one pair of wings, three pairs of long hair-like legs, and specialized, highly elongated, piercing-sucking mouthparts. All mosquitoes drink nectar from flowers; females of many species have adapted to also drink blood. The group diversified during the Cretaceous period. Evolutionary biologists view mosquitoes as micropredators, small animals that parasitise larger ones by drinking their blood without immediately killing them. Medical parasitologists view mosquitoes as vectors of disease, carrying protozoan parasites or bacterial or viral pathogens from one host to another.

The mosquito life cycle consists of four stages: egg, larva, pupa, and adult. Eggs are laid on the water surface; they hatch into motile larvae that feed on aquatic algae and organic material. These larvae are important food sources for many freshwater animals, such as dragonfly nymphs, many fish, and some birds. Adult females of many species have mouthparts adapted to pierce the skin of a host and feed on blood of a wide range of vertebrate hosts, and some invertebrates, primarily other arthropods. Some species only produce eggs after a blood meal.

Mutualism describes the ecological interaction between two or more species where each species has a net benefit. Mutualism is a common type of ecological interaction. Prominent examples are:

• the nutrient exchange between vascular plants and mycorrhizal fungi,
• the fertilization of flowering plants by pollinators,
• the ways plants use fruits and edible seeds to encourage animal aid in seed dispersal, and
• the way corals become photosynthetic with the help of the microorganism zooxanthellae.

Mutualism can be contrasted with interspecific competition, in which each species experiences reduced fitness, and exploitation, and with parasitism, in which one species benefits at the expense of the other. However, mutualism may evolve from interactions that began with imbalanced benefits, such as parasitism.