Panchen Lama in the context of Khedrup Gelek Pelzang

Lama (Tibetan: བླ་མ་, Wylie: bla-ma) is a title bestowed to a realized practitioner of the Dharma in Tibetan Buddhism. Not all monks are lamas, while nuns and female practitioners can be recognized and entitled as lamas. The Tibetan word la-ma means "high mother", and reflects the qualities of the person entitled as a lama.

Historically and currently, the term is bestowed on venerated spiritual masters andmay be part of a specific lineage title such as the Dalai Lama and the Panchen Lama, lineages of reincarnate high Tulkus.

Bogd Khan (13 October 1869 – 20 May 1924) was the khan of the Bogd Khanate of Mongolia from 1911 to 1924, following the state's de facto independence from the Qing dynasty of China after the Xinhai Revolution. Born in Tibet, he was the third most important person in the Tibetan Buddhist hierarchy as the 8th Jebtsundamba Khutuktu, below only the Dalai Lama and Panchen Lama, and therefore also known as the "Bogdo Lama". He was the spiritual leader of Tibetan Buddhism in the Bogd Khaganate. His wife Tsendiin Dondogdulam, the Ekh Dagina ('Dakini Mother'), was believed to be a manifestation of White Tara.
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A tulku (Tibetan: སྤྲུལ་སྐུ་, Wylie: sprul sku, ZWPY: Zhügu, also tülku, trulku) is an individual recognized as the reincarnation of a previous spiritual master (lama), and expected to be reincarnated, in turn, after death. The tulku is a distinctive and significant aspect of Tibetan Buddhism, embodying the concept of enlightened beings taking corporeal forms to continue the lineage of specific teachings. The term "tulku" is a loanword from Tibetan སྤྲུལ་སྐུ ("sprul sku"), which originally referred to an emperor or ruler taking human form on Earth, signifying a divine incarnation. Over time, it evolved within Tibetan Buddhism to denote the corporeal existence of certain highly accomplished Buddhist masters whose purpose was to ensure the preservation and transmission of a particular lineage.

The tulku system originated in Tibet, particularly associated with the recognition of the second Karmapa in the 13th century. Since then, numerous tulku lineages have been established, with each tulku having a distinctive role in preserving and propagating specific teachings. Other high-profile examples of tulkus include the Dalai Lamas, the Panchen Lamas, the Samding Dorje Phagmos, Khyentses, the Zhabdrung Rinpoches, and the Kongtruls.

Khedrup Gelek Pelzang, 1st Panchen Lama (1385–1438 CE) – better known as Khedrup Je –  was one of the main disciples of Je Tsongkhapa, whose reforms to Atiśa's Kadam tradition are considered the beginnings of the Gelug school of Tibetan Buddhism.

Khedrub Je is considered to be an emanation of Manjusri, the Buddha of Wisdom.