Oshikoto Region in the context of Lake Otjikoto

Etosha National Park is a national park in northwestern Namibia and one of the largest national parks in Africa. It was proclaimed a game reserve in March 1907 in Ordinance 88 by the Governor of German South West Africa, Friedrich von Lindequist. It was designated as Wildschutzgebiet in 1958, and was awarded the status of national park in 1967, by an act of parliament of the Republic of South Africa. It spans an area of 22,270 km (8,600 sq mi) and was named after the large Etosha pan which is almost entirely within the park. With an area of 4,760 km (1,840 sq mi), the Etosha pan covers 23% of the total area of the national park. The area is home to hundreds of species of mammals, birds and reptiles, including several threatened and endangered species such as the black rhinoceros. Sixty-one black rhinoceros were killed during poaching in Namibia during 2022, 46 of which were killed in Etosha.

The park is located in the Kunene region and shares boundaries with the regions of Oshana, Oshikoto and Otjozondjupa.

Ondangwa (earlier spelling Ondangua) is a town in the Oshana Region of northern Namibia, bordering the Oshikoto Region. It had a population of 30,364 people in 2023.

Ondangwa was first established as a mission station of the Finnish Missionary Society (the FMS) in 1890. In 1914, it became a local seat of government. Today, Ondangwa is a fast-growing town and the district capital of the Ondangwa electoral constituency.

Tsumeb (Otjiherero: Okavisume; Khoekhoe: ǂAixorobes) is a town of around 35,000 inhabitants and the largest town and the former capital of the Oshikoto region in northern Namibia.

Tsumeb, since its founding in 1905, has been primarily a mining town. The town is the site of a deep mine (the lower workings now closed) whose ore deposits with respect to variety, rarity and aesthetics of minerals have been listed among 100 geological heritage sites around the world by the International Union of Geological Sciences (IUGS).