Occipital lobe in the context of "Motion perception"

The human brain is the central organ of the nervous system, and with the spinal cord, comprises the central nervous system. It consists of the cerebrum, the brainstem and the cerebellum. The brain controls most of the activities of the body, processing, integrating, and coordinating the information it receives from the sensory nervous system. The brain integrates sensory information and coordinates instructions sent to the rest of the body.

The cerebrum, the largest part of the human brain, consists of two cerebral hemispheres. Each hemisphere has an inner core composed of white matter, and an outer surface – the cerebral cortex – composed of grey matter. The cortex has an outer layer, the neocortex, and an inner allocortex. The neocortex is made up of six neuronal layers, while the allocortex has three or four. Each hemisphere is divided into four lobes – the frontal, parietal, temporal, and occipital lobes. The frontal lobe is associated with executive functions including self-control, planning, reasoning, and abstract thought, while the occipital lobe is dedicated to vision. Within each lobe, cortical areas are associated with specific functions, such as the sensory, motor, and association regions. Although the left and right hemispheres are broadly similar in shape and function, some functions are associated with one side, such as language in the left and visual-spatial ability in the right. The hemispheres are connected by commissural nerve tracts, the largest being the corpus callosum.

The visual cortex of the brain is the area of the cerebral cortex that processes visual information. It is located in the occipital lobe. Sensory input originating from the eyes travels through the lateral geniculate nucleus in the thalamus and then reaches the visual cortex. The area of the visual cortex that receives the sensory input from the lateral geniculate nucleus is the primary visual cortex, also known as visual area 1 (V1), Brodmann area 17, or the striate cortex. The extrastriate areas consist of visual areas 2, 3, 4, and 5 (also known as V2, V3, V4, and V5, or Brodmann area 18 and all Brodmann area 19).

Both hemispheres of the brain include a visual cortex; the visual cortex in the left hemisphere receives signals from the right visual field, and the visual cortex in the right hemisphere receives signals from the left visual field.

The occipital bone (/ˌɒkˈsɪpɪtəl/) is a cranial dermal bone and the main bone of the occiput (back and lower part of the skull). It is trapezoidal in shape and curved on itself like a shallow dish. The occipital bone lies over the occipital lobes of the cerebrum. At the base of the skull in the occipital bone, there is a large oval opening called the foramen magnum, which allows the passage of the spinal cord.

Like the other cranial bones, it is classed as a flat bone. Due to its many attachments and features, the occipital bone is described in terms of separate parts. From its front to the back is the basilar part, also called the basioccipital, at the sides of the foramen magnum are the lateral parts, also called the exoccipitals, and the back is named as the squamous part. The basilar part is a thick, somewhat quadrilateral piece in front of the foramen magnum and directed towards the pharynx. The squamous part is the curved, expanded plate behind the foramen magnum and is the largest part of the occipital bone.

The two-streams hypothesis is a model of the neural processing of vision as well as hearing. The hypothesis, given its initial characterisation in a paper by David Milner and Melvyn A. Goodale in 1992, argues that humans possess two distinct visual systems. Recently there seems to be evidence of two distinct auditory systems as well. As visual information exits the occipital lobe, and as sound leaves the phonological network, it follows two main pathways, or "streams". The ventral stream (also known as the "what pathway") leads to the temporal lobe, which is involved with object and visual identification and recognition. The dorsal stream (or, "where pathway") leads to the parietal lobe, which is involved with processing the object's spatial location relative to the viewer and with speech repetition.

The line of Gennari (also called the "band" or "stria" of Gennari) is a band of myelinated axons that runs parallel to the surface of the cerebral cortex on the banks of the calcarine fissure in the occipital lobe. This formation is visible to the naked eye as a white strip running through the cortical grey matter, and is the reason the V1 in primates is also referred to as the "striate cortex." The line of Gennari is due to dense axonal input from the thalamus to layer IV of visual cortex. It is the name given to the enlarged external band of Baillarger. The structure is named for its discoverer, Francesco Gennari, who first observed it in 1776 as a medical student at the University of Parma. He described it in a book which he published in 1782. Although non-primate species have areas that are designated primary visual cortex, some (if not all) lack a stria of Gennari.

Vicq d’Azyr published the stripes in Traité d'anatomie (1786), and for a while it was known as the stripe of Vicq d’Azyr.

The extrastriate cortex is the region of the occipital cortex of the mammalian brain located next to the primary visual cortex. Primary visual cortex (V1) is also named striate cortex because of its striped appearance in the microscope. The extrastriate cortex encompasses multiple functional areas, including V3, V4, V5/MT, which is sensitive to motion, or the extrastriate body area (EBA) used in the perception of human bodies.

Anton syndrome, also known as Anton–Babinski syndrome and visual anosognosia, is a rare symptom of brain damage occurring in the occipital lobe. Those who have it are cortically blind, but affirm, often quite adamantly and in the face of clear evidence of their blindness, that they are capable of seeing. Failing to accept being blind, people with Anton syndrome dismiss evidence of their condition and employ confabulation to fill in the missing sensory input. It is named after the neurologist Gabriel Anton. Only 28 cases have been published.

Frontotemporal lobar degeneration (FTLD) is a pathological process that occurs in frontotemporal dementia. It is characterized by atrophy in the frontal lobe and temporal lobe of the brain, with sparing of the parietal and occipital lobes.

Common proteinopathies that are found in FTLD include the accumulation of tau proteins and TAR DNA-binding protein 43 (TDP-43). Mutations in the C9orf72 gene have been established as a major genetic contribution of FTLD, although defects in the granulin (GRN) and microtubule-associated proteins (MAPs) are also associated with it.