Nuclear medicine in the context of "TRIUMF"

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⭐ Core Definition: Nuclear medicine

Nuclear medicine (nuclear radiology) is a medical specialty involving the application of radioactive substances in the diagnosis and treatment of disease. Nuclear imaging is, in a sense, radiology done inside out, because it records radiation emitted from within the body rather than radiation that is transmitted through the body from external sources like X-ray generators. In addition, nuclear medicine scans differ from radiology, as the emphasis is not on imaging anatomy, but on the function. For this reason, it is called a physiological imaging modality. Single photon emission computed tomography (SPECT) and positron emission tomography (PET) scans are the two most common imaging modalities in nuclear medicine.

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Nuclear medicine in the context of Radioactive waste

Radioactive waste is a type of hazardous waste that contains radioactive material. It is a result of many activities, including nuclear medicine, nuclear research, nuclear power generation, nuclear decommissioning, rare-earth mining, and nuclear weapons reprocessing. The storage and disposal of radioactive waste is regulated by government agencies in order to protect human health and the environment.

Radioactive waste is broadly classified into 3 categories: low-level waste (LLW), such as paper, rags, tools, clothing, which contain small amounts of mostly short-lived radioactivity; intermediate-level waste (ILW), which contains higher amounts of radioactivity and requires some shielding; and high-level waste (HLW), which is highly radioactive and hot due to decay heat, thus requiring cooling and shielding.

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Nuclear medicine in the context of Nuclear technology

Nuclear technology is technology that involves the nuclear reactions of atomic nuclei. Among the notable nuclear technologies are nuclear reactors, nuclear medicine and nuclear weapons. It is also used, among other things, in smoke detectors and gun sights.

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Nuclear medicine in the context of Atomic age

The Atomic Age, also known as the Atomic Era, is the period of history following the detonation of the first nuclear weapon, The Gadget at the Trinity test in New Mexico on 16 July 1945 during World War II. Although nuclear chain reactions had been hypothesized in 1933 and the first artificial self-sustaining nuclear chain reaction (Chicago Pile-1) had taken place in December 1942, the Trinity test and the ensuing bombings of Hiroshima and Nagasaki that ended World War II represented the first large-scale use of nuclear technology and ushered in profound changes in sociopolitical thinking and the course of technological development.

While atomic power was promoted for a time as the epitome of progress and modernity, entering into the nuclear power era also entailed frightful implications of nuclear warfare, the Cold War, mutual assured destruction, nuclear proliferation, the risk of nuclear disaster (potentially as extreme as anthropogenic global nuclear winter), as well as beneficial civilian applications in nuclear medicine. It is no easy matter to fully segregate peaceful uses of nuclear technology from military or terrorist uses (such as the fabrication of dirty bombs from radioactive waste), which complicated the development of a global nuclear-power export industry right from the outset.

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Nuclear medicine in the context of Nuclear reactor

A nuclear reactor is a device used to sustain a controlled fission nuclear chain reaction. They are used for commercial electricity, marine propulsion, weapons production and research. Fissile nuclei (primarily uranium-235 or plutonium-239) absorb single neutrons and split, releasing energy and multiple neutrons, which can induce further fission. Reactors stabilize this, regulating neutron absorbers and moderators in the core. Fuel efficiency is exceptionally high; low-enriched uranium is 120,000 times more energy-dense than coal.

Heat from nuclear fission is passed to a working fluid coolant. In commercial reactors, this drives turbines and electrical generator shafts. Some reactors are used for district heating, and isotope production for medical and industrial use.

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Nuclear medicine in the context of Scintigraphy

Scintigraphy (from Latin scintilla, "spark"), also known as a gamma scan, is a diagnostic test in nuclear medicine, where radioisotopes attached to drugs that travel to a specific organ or tissue (radiopharmaceuticals) are taken internally and the emitted gamma radiation is captured by gamma cameras, which are external detectors that form two-dimensional images in a process similar to the capture of X-ray images. In contrast, SPECT and positron emission tomography (PET) form 3-dimensional images and are therefore classified as separate techniques from scintigraphy, although they also use gamma cameras to detect internal radiation. Scintigraphy is unlike a diagnostic X-ray where external radiation is passed through the body to form an image.

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Nuclear medicine in the context of Single-photon emission computed tomography

Single-photon emission computed tomography (SPECT, or less commonly, SPET) is a nuclear medicine tomographic imaging technique using gamma rays. It is very similar to conventional nuclear medicine planar imaging using a gamma camera (that is, scintigraphy), but is able to provide true 3D information. This information is typically presented as cross-sectional slices through the patient, but can be freely reformatted or manipulated as required.

The technique needs delivery of a gamma-emitting radioisotope (a radionuclide) into the patient, normally through injection into the bloodstream. On occasion, the radioisotope is a simple soluble dissolved ion, such as an isotope of gallium(III). Usually, however, a marker radioisotope is attached to a specific ligand to create a radioligand, whose properties bind it to certain types of tissues. This marriage allows the combination of ligand and radiopharmaceutical to be carried and bound to a place of interest in the body, where the ligand concentration is seen by a gamma camera.

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Nuclear medicine in the context of Radiology

Radiology (/ˌrdiˈɒlədʒi/ RAY-dee-AHL-ə-jee) is the medical specialty that uses medical imaging to diagnose diseases and guide treatment within the bodies of humans and other animals. It began with radiography (which is why its name has a root referring to radiation), but today it includes all imaging modalities. This includes technologies that use no ionizing electromagnetic radiation, such as ultrasonography and magnetic resonance imaging (MRI), as well as others that do use radiation, such as computed tomography (CT), fluoroscopy, and nuclear medicine including positron emission tomography (PET). Interventional radiology is the performance of usually minimally invasive medical procedures with the guidance of imaging technologies such as those mentioned above.

The modern practice of radiology involves a team of several different healthcare professionals. A radiologist, who is a medical doctor with specialized post-graduate training, interprets medical images, communicates these findings to other physicians through reports or verbal communication, and uses imaging to perform minimally invasive medical procedures The nurse is involved in the care of patients before and after imaging or procedures, including administration of medications, monitoring of vital signs and monitoring of sedated patients. The radiographer, also known as a radiologic technologist in countries such as the United States and Canada, is a specialized healthcare professional who performs radiographic procedures and radiation therapy for the diagnosis and treatment of diseases such as cancer. The images produced through radiographic procedures are used for interpretation by radiologists, and depending on their education, training, and the regulations of the country in which they practice, radiographers in some regions also have an extended role in image interpretation and reporting.

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Nuclear medicine in the context of Physics of magnetic resonance imaging

Magnetic resonance imaging (MRI) is a medical imaging technique mostly used in radiology and nuclear medicine in order to investigate the anatomy and physiology of the body, and to detect pathologies including tumors, inflammation, neurological conditions such as stroke, disorders of muscles and joints, and abnormalities in the heart and blood vessels among other things. Contrast agents may be injected intravenously or into a joint to enhance the image and facilitate diagnosis. Unlike CT and X-ray, MRI uses no ionizing radiation and is, therefore, a safe procedure suitable for diagnosis in children and repeated runs. Patients with specific non-ferromagnetic metal implants, cochlear implants, and cardiac pacemakers nowadays may also have an MRI in spite of effects of the strong magnetic fields. This does not apply on older devices, and details for medical professionals are provided by the device's manufacturer.

Certain atomic nuclei are able to absorb and emit radio frequency energy when placed in an external magnetic field. In clinical and research MRI, hydrogen atoms are most often used to generate a detectable radio-frequency signal that is received by antennas close to the anatomy being examined. Hydrogen atoms are naturally abundant in people and other biological organisms, particularly in water and fat. For this reason, most MRI scans essentially map the location of water and fat in the body. Pulses of radio waves excite the nuclear spin energy transition, and magnetic field gradients localize the signal in space. By varying the parameters of the pulse sequence, different contrasts may be generated between tissues based on the relaxation properties of the hydrogen atoms therein.

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