Northeast Africa in the context of "Incense route"

In classical antiquity, the Hellenistic period covers the time in Greek, Eastern Mediterranean, and West Asian (or Middle Eastern) history following Classical Greece, between the death of Alexander the Great in 323 BC and the death of Cleopatra VII in 30 BC, in which these regions were under the influence of Greek leadership, culture, and language. The Hellenistic period was followed by the ascendancy of the Roman Empire, the Battle of Actium in 31 BC, and the Roman conquest of Ptolemaic Egypt the following year, which eliminated the last major Hellenistic kingdom. Its name stems from the Ancient Greek word Hellas (Ἑλλάς, Hellás), which was gradually recognized as the name for Greece, from which the modern historiographical term Hellenistic was derived. The term "Hellenistic" is to be distinguished from "Hellenic" in that the latter refers to Greece itself, while the former encompasses all the ancient territories of the period that had come under significant Greek influence, particularly the Hellenized Ancient Near East, after the conquests of Alexander the Great.

After the Macedonian conquest of the Achaemenid Empire in 330 BC and its disintegration shortly thereafter in the Partition of Babylon and subsequent Wars of the Diadochi, Hellenistic kingdoms were established throughout West Asia (Seleucid Empire, Kingdom of Pergamon), Northeast Africa (Ptolemaic Kingdom) and South Asia (Greco-Bactrian Kingdom, Indo-Greek Kingdom). This resulted in an influx of Greek colonists and the export of Greek culture and language to these new realms, a breadth spanning as far as modern-day India. These new Greek kingdoms were also influenced by regional indigenous cultures, adopting local practices which were deemed beneficial, necessary, or convenient. Hellenistic culture thus represents a fusion of the ancient Greek world with that of the Western Asian, Northeastern African, and Southwestern Asian worlds. The consequence of this mixture gave rise to a common Attic-based Greek dialect, known as Koine Greek, which became the lingua franca throughout the ancient world.

Egypt, officially the Arab Republic of Egypt, is a country spanning the northeast corner of Africa and southwest corner of Asia via the Sinai Peninsula. It is bordered by the Mediterranean Sea to the north, Palestine and Israel to the northeast, the Red Sea to the east, Sudan to the south, and Libya to the west; the Gulf of Aqaba in the northeast separates Egypt from Jordan and Saudi Arabia. Cairo is the capital, largest city, and leading cultural center, while Alexandria is the second-largest city and an important hub of industry and tourism. With over 107 million inhabitants, Egypt is the third-most populous country in Africa and 15th-most populated in the world.

Egypt has one of the longest histories of any country, tracing its heritage along the Nile Delta back to the 6th–4th millennia BCE. Considered a cradle of civilisation, Ancient Egypt saw some of the earliest developments of writing, agriculture, urbanisation, organised religion and central government. Egypt was an early and important centre of Christianity, later adopting Islam from the seventh century onwards. Alexandria, Egypt's former capital and currently second largest city, was a hub of global knowledge through its Library. Cairo became the capital of the Fatimid Caliphate in the tenth century and of the subsequent Mamluk Sultanate in the 13th century. Egypt then became part of the Ottoman Empire in 1517, until its local ruler Muhammad Ali established modern Egypt as an autonomous Khedivate in 1867. The country was then occupied by the British Empire along with Sudan and gained independence in 1922 as a monarchy.

The Levant (/ləˈvænt/ lə-VANT, US also /ləˈvɑːnt/ lə-VAHNT) is a subregion of West Asia along the Eastern Mediterranean, that forms part of the Middle East. The term is often used in conjunction with historical or cultural references.

In its narrowest sense, used in archaeology and other contexts, the Levant refers to Cyprus and land bordering the Mediterranean Sea in West Asia that includes the Syria region, Lebanon, Jordan, Palestine, Israel, and south Cilicia (Turkey). In its widest historical sense, the Levant included all the Eastern Mediterranean; extending from Greece to Egypt and Cyrenaica (Eastern Libya). The Levant represents the land bridge between Africa and Eurasia, has been described as the crossroads of West Asia, Eastern Mediterranean, and Northeast Africa, and geologically as the "northwest of the Arabian plate".

Ancient Egypt was a cradle of civilization concentrated along the lower reaches of the Nile River in Northeast Africa. It emerged from prehistoric Egypt around 3150 BC (according to conventional Egyptian chronology), when Upper and Lower Egypt were amalgamated by Menes, who is believed by the majority of Egyptologists to have been the same person as Narmer. The history of ancient Egypt unfolded as a series of stable kingdoms interspersed by the "Intermediate Periods" of relative instability. These stable kingdoms existed in one of three periods: the Old Kingdom of the Early Bronze Age; the Middle Kingdom of the Middle Bronze Age; or the New Kingdom of the Late Bronze Age.

The pinnacle of ancient Egyptian power was achieved during the New Kingdom, which extended its rule to much of Nubia and a considerable portion of the Levant. After this period, Egypt entered an era of slow decline. Over the course of its history, it was invaded or conquered by a number of foreign civilizations, including the Hyksos, the Kushites, the Assyrians, the Persians, and the Greeks and then the Romans. The end of ancient Egypt is variously defined as occurring with the end of the Late Period during the Wars of Alexander the Great in 332 BC or with the end of the Greek-ruled Ptolemaic Kingdom during the Roman conquest of Egypt in 30 BC. In AD 642, the Arab conquest of Egypt brought an end to the region's millennium-long Greco-Roman period.

Darius I (Old Persian: 𐎭𐎠𐎼𐎹𐎺𐎢𐏁 Dārayavaʰuš; c. 550 – 486 BCE), commonly known as Darius the Great, was the third King of Kings of the Achaemenid Empire, reigning from 522 BCE until his death in 486 BCE. He ruled the empire at its territorial peak, when it included much of West Asia, parts of the Balkans (Thrace–Macedonia and Paeonia) and the Caucasus, most of the Black Sea's coastal regions, Central Asia, the Indus Valley in the far east, and portions of North Africa and Northeast Africa including Egypt (Mudrâya), eastern Libya, and coastal Sudan.

Darius ascended the throne after overthrowing the Achaemenid monarch Bardiya (or Smerdis), who he claimed was in fact an imposter named Gaumata. The new king met with rebellions throughout the empire but quelled each of them; a major event of Darius's career described in Greek historiography was his punitive expedition against Athens and Eretria for their participation in the Ionian Revolt.