Nombre de Dios (Spanish: "Name of God") is a city and corregimiento in Santa Isabel District, Colón Province, Panama, on the Atlantic coast of Panama in the Colón Province. Founded as a Spanish colony in 1510 by Diego de Nicuesa, it was one of the first European settlements on the Isthmus of Panama.
A major port of call for Spanish silver shipments during the 16th century, it was difficult to defend and was virtually abandoned by the Spanish after 1600. As of 2010, it had a population of 1,130 people.