Nocebo in the context of Placebo


Nocebo in the context of Placebo

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⭐ Core Definition: Nocebo

A nocebo effect is said to occur when a patient's expectations for a treatment cause the treatment to have a worse effect than it otherwise would have. For example, when a patient anticipates a side effect of a medication, they can experience that effect even if the "medication" is actually an inert substance. The complementary concept, the placebo effect, is said to occur when expectations improve an outcome.

More generally, the nocebo effect is falling ill simply by consciously or subconsciously anticipating a harmful event. This definition includes anticipated events other than medical treatment. It has been applied to Havana syndrome, where purported victims were anticipating attacks by foreign adversaries. This definition also applies to cases of electromagnetic hypersensitivity.

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Nocebo in the context of Therapeutic effect

Therapeutic effect refers to the response(s) after a treatment of any kind, the results of which are judged to be useful or favorable. This is true whether the result was expected, unexpected, or even an unintended consequence. An adverse effect (including nocebo) is the converse and refers to harmful or undesired response(s). What constitutes a therapeutic effect versus a side effect is a matter of both the nature of the situation and the goals of treatment. No inherent difference separates therapeutic and undesired side effects; both responses are behavioral/physiologic changes that occur as a response to the treatment strategy or agent.

View the full Wikipedia page for Therapeutic effect
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