The 1669 eruption of Mount Etna is the largest-recorded historical eruption of that volcano on the east coast of Sicily, Italy. After several weeks of increasing seismic activity that damaged the town of Nicolosi and other settlements, an eruption fissure opened on the southeastern flank of Etna during the night of 10–11 March. Several more fissures became active during 11 March, erupting pyroclastics and tephra that fell over Sicily and accumulated to form the Monti Rossi scoria cone.
Lava disgorged from the eruption fissures and flowed southwards away from the vent, burying farmland and a number of towns during March and April, eventually covering 37–40 square kilometres (14–15 sq mi). The inhabitants of the towns fled to the city of Catania and sought refuge there; religious ceremonies were held in the city to implore the end of the eruption. In early April a branch of the lava flow advanced towards the city, and on the 1 or 16 April it reached the city walls, provoking the flight of many of its inhabitants. The city walls held up the lava, which began to flow into the Ionian Sea. More than two weeks later, parts of the flow surmounted the walls and penetrated Catania but did not cause much damage. The eruption ended in July.